| Literature DB >> 12127522 |
William J Pitts1, Junqing Guo, T G Murali Dhar, Zhongqi Shen, Henry H Gu, Scott H Watterson, Mark S Bednarz, Bang Chi Chen, Joel C Barrish, Donna Bassolino, Daniel Cheney, Catherine A Fleener, Katherine A Rouleau, Diane L Hollenbaugh, Edwin J Iwanowicz.
Abstract
A series of novel triazine-based small molecule inhibitors (IV) of inosine monophosphate dehydrogenase was prepared. The synthesis and the structure-activity relationships (SAR) derived from in vitro studies are described.Entities:
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Year: 2002 PMID： 12127522 DOI： 10.1016/s0960-894x(02)00351-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823