| Literature DB >> 12126228 |
Abstract
Separation of distinct body, organ and tissue compartments, and maintenance of epithelial cell polarity require tight junctions (TJ)-cell-cell junctions located in the apicolateral regions of epithelial and endothelial cells. Studies on the protein components of vertebrate TJ have revealed an intricate network of membrane, sub-membrane, cytoskeletal, and signalling molecules. How these molecules functionally interact to provide TJ with their functions, and what roles these molecules play in control of cell growth and differentiation is a fundamental problem in cell biology.Mesh:
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Year: 2002 PMID: 12126228 DOI: 10.1080/09687680210129236
Source DB: PubMed Journal: Mol Membr Biol ISSN: 0968-7688 Impact factor: 2.857