Literature DB >> 12124167

Myc-Is this the oncogene from Hell?

Laura Soucek1, Gerard Evan.   

Abstract

A new paper implicates the Myc oncoprotein in the direct induction of DNA damage and consequent genome instability in cultured cells. However, it is less clear whether Myc induces the same genetic pandemonium in vivo.

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Year:  2002        PMID: 12124167     DOI: 10.1016/s1535-6108(02)00077-6

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  21 in total

1.  Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression.

Authors:  Asa Karlsson; Debabrita Deb-Basu; Athena Cherry; Stephanie Turner; James Ford; Dean W Felsher
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-08       Impact factor: 11.205

2.  Multiple mutations contribute to repression by the v-Erb A oncoprotein.

Authors:  Sangho Lee; Martin L Privalsky
Journal:  Oncogene       Date:  2005-10-13       Impact factor: 9.867

3.  ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

Authors:  Raju V Pusapati; Robert J Rounbehler; SungKi Hong; John T Powers; Mingshan Yan; Kaoru Kiguchi; Mark J McArthur; Paul K Wong; David G Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-23       Impact factor: 11.205

4.  Myc: the beauty and the beast.

Authors:  Amanda R Wasylishen; Linda Z Penn
Journal:  Genes Cancer       Date:  2010-06

5.  Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.

Authors:  Javier A Menendez; Tomás Alarcón; Jorge Joven
Journal:  Cell Cycle       Date:  2014-02-03       Impact factor: 4.534

6.  Werner syndrome protein limits MYC-induced cellular senescence.

Authors:  Carla Grandori; Kou-Juey Wu; Paula Fernandez; Celine Ngouenet; Jonathan Grim; Bruce E Clurman; Michael J Moser; Junko Oshima; David W Russell; Karen Swisshelm; Scott Frank; Bruno Amati; Riccardo Dalla-Favera; Raymond J Monnat
Journal:  Genes Dev       Date:  2003-07-01       Impact factor: 11.361

Review 7.  The ups and downs of Myc biology.

Authors:  Laura Soucek; Gerard I Evan
Journal:  Curr Opin Genet Dev       Date:  2009-12-03       Impact factor: 5.578

8.  MYC levels govern hematopoietic tumor type and latency in transgenic mice.

Authors:  Darrin P Smith; Mary L Bath; Donald Metcalf; Alan W Harris; Suzanne Cory
Journal:  Blood       Date:  2006-03-14       Impact factor: 22.113

9.  Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.

Authors:  Richard A Woo; Randy Y C Poon
Journal:  Genes Dev       Date:  2004-06-01       Impact factor: 11.361

10.  A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response.

Authors:  Sanjay Chandriani; Eirik Frengen; Victoria H Cowling; Sarah A Pendergrass; Charles M Perou; Michael L Whitfield; Michael D Cole
Journal:  PLoS One       Date:  2009-08-19       Impact factor: 3.240

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