Literature DB >> 21779457

Myc: the beauty and the beast.

Amanda R Wasylishen1, Linda Z Penn.   

Abstract

The iconic history of the Myc oncoprotein encompasses 3 decades of intense scientific discovery. There is no question that Myc has been a pioneer, advancing insight into the molecular basis of cancer as well as functioning as a critical control center for several diverse biological processes and regulatory mechanisms. This narrative chronicles the journey and milestones that have defined the understanding of Myc, and it provides an opportunity to consider future directions in this challenging yet rewarding field.

Entities:  

Keywords:  Myc; cancer; cell cycle; oncogene; transcription

Year:  2010        PMID： 21779457      PMCID： PMC3092215          DOI： 10.1177/1947601910378024

Source DB:  PubMed          Journal:  Genes Cancer        ISSN： 1947-6019


  168 in total

1.  An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants.

Authors:  R J Miltenberger; K A Sukow; P J Farnham
Journal:  Mol Cell Biol       Date:  1995-05       Impact factor: 4.272

2.  Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas.

Authors:  K Bhatia; G Spangler; G Gaidano; N Hamdy; R Dalla-Favera; I Magrath
Journal:  Blood       Date:  1994-08-01       Impact factor: 22.113

Review 3.  The molecular genetics of cellular oncogenes.

Authors:  H E Varmus
Journal:  Annu Rev Genet       Date:  1984       Impact factor: 16.830

4.  c-Myc induces the expression and activity of ornithine decarboxylase.

Authors:  A J Wagner; C Meyers; L A Laimins; N Hay
Journal:  Cell Growth Differ       Date:  1993-11

Review 5.  Rethinking the Warburg effect with Myc micromanaging glutamine metabolism.

Authors:  Chi V Dang
Journal:  Cancer Res       Date:  2010-01-19       Impact factor: 12.701

6.  Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage.

Authors:  G M Brodeur; R C Seeger; M Schwab; H E Varmus; J M Bishop
Journal:  Science       Date:  1984-06-08       Impact factor: 47.728

7.  Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression.

Authors:  Daniel Y L Mao; John D Watson; Pearlly S Yan; Dalia Barsyte-Lovejoy; Fereshteh Khosravi; W Wei-Lynn Wong; Peggy J Farnham; Tim H-M Huang; Linda Z Penn
Journal:  Curr Biol       Date:  2003-05-13       Impact factor: 10.834

8.  Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas.

Authors:  S Crews; R Barth; L Hood; J Prehn; K Calame
Journal:  Science       Date:  1982-12-24       Impact factor: 47.728

9.  In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors:  Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

10.  L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer.

Authors:  M M Nau; B J Brooks; J Battey; E Sausville; A F Gazdar; I R Kirsch; O W McBride; V Bertness; G F Hollis; J D Minna
Journal:  Nature       Date:  1985 Nov 7-13       Impact factor: 49.962
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  29 in total

1.  Epigenetic reprogramming of Myc target genes.

Authors:  Stefano Amente; Luigi Lania; Barbara Majello
Journal:  Am J Cancer Res       Date:  2011-02-06       Impact factor: 6.166

2.  SUMO-activating SAE1 transcription is positively regulated by Myc.

Authors:  Stefano Amente; Miriam Lubrano Lavadera; Giacomo Di Palo; Barbara Majello
Journal:  Am J Cancer Res       Date:  2012-04-21       Impact factor: 6.166

3.  CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway.

Authors:  Kazuya Fukasawa; Takuya Kadota; Tetsuhiro Horie; Kazuya Tokumura; Ryuichi Terada; Yuka Kitaguchi; Gyujin Park; Shinsuke Ochiai; Sayuki Iwahashi; Yasuka Okayama; Manami Hiraiwa; Takanori Yamada; Takashi Iezaki; Katsuyuki Kaneda; Megumi Yamamoto; Tatsuya Kitao; Hiroaki Shirahase; Masaharu Hazawa; Richard W Wong; Tomoki Todo; Atsushi Hirao; Eiichi Hinoi
Journal:  Oncogene       Date:  2021-03-16       Impact factor: 9.867

4.  Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters.

Authors:  Chui-Sun Yap; Abigail L Peterson; Gastone Castellani; John M Sedivy; Nicola Neretti
Journal:  Cell Cycle       Date:  2011-07-01       Impact factor: 4.534

5.  Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.

Authors:  John K Simmons; Aleksandra M Michalowski; Benjamin J Gamache; Wendy DuBois; Jyoti Patel; Ke Zhang; Joy Gary; Shuling Zhang; Snehal Gaikwad; Daniel Connors; Nicholas Watson; Elena Leon; Jin-Qiu Chen; W Michael Kuehl; Maxwell P Lee; Adriana Zingone; Ola Landgren; Peter Ordentlich; Jing Huang; Beverly A Mock
Journal:  Mol Cancer Ther       Date:  2017-05-18       Impact factor: 6.261

Review 6.  Chemical modulation of transcription factors.

Authors:  Bianca Wiedemann; Jörn Weisner; Daniel Rauh
Journal:  Medchemcomm       Date:  2018-07-11       Impact factor: 3.597

7.  Pdcd4 knockdown up-regulates MAP4K1 expression and activation of AP-1 dependent transcription through c-Myc.

Authors:  Qing Wang; Yan Zhang; Hsin-Sheng Yang
Journal:  Biochim Biophys Acta       Date:  2012-07-16

8.  Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.

Authors:  Valentina Folgiero; Cristina Sorino; Matteo Pallocca; Francesca De Nicola; Frauke Goeman; Valentina Bertaina; Luisa Strocchio; Paolo Romania; Angela Pitisci; Simona Iezzi; Valeria Catena; Tiziana Bruno; Georgios Strimpakos; Claudio Passananti; Elisabetta Mattei; Giovanni Blandino; Franco Locatelli; Maurizio Fanciulli
Journal:  EMBO Rep       Date:  2018-01-24       Impact factor: 8.807

9.  Critical role of Shp2 in tumor growth involving regulation of c-Myc.

Authors:  Yuan Ren; Zhengming Chen; Liwei Chen; Bin Fang; Hla Win-Piazza; Eric Haura; John M Koomen; Jie Wu
Journal:  Genes Cancer       Date:  2010-10

10.  c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells.

Authors:  Zuqin Nie; Gangqing Hu; Gang Wei; Kairong Cui; Arito Yamane; Wolfgang Resch; Ruoning Wang; Douglas R Green; Lino Tessarollo; Rafael Casellas; Keji Zhao; David Levens
Journal:  Cell       Date:  2012-09-28       Impact factor: 41.582
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