Effects of Aframomum melegueta and Piper guineense on sexual behaviour of male rats.

The effects of aqueous extracts of Aframomum melegueta and Piper guineense on the sexual behaviour of male rats were studied, considering many criteria, such as penile erection, copulatory behaviour and orientation activities towards themselves (genital grooming) and female rats (ano-genital sniffing, mounting). For 8 days different groups of rats received a daily administration of distilled water (control) or a plant extract: A. melegueta at 115 mg/kg or P. guineense at 122.5 mg/kg. Both plant extracts stimulated male sexual behaviour. In fact, A. melegueta and P. guineense significantly increased penile erection index, and the frequencies of intromission and ejaculation. These plant extracts were found to enhance the orientation of males towards females by increasing mounting and ano-genital investigatory behaviour. Results of this study showed that A. melegueta and P. guineense modified the sexual behaviour of male rats by increasing sexual arousal. Copyright 2002 Lippincott Williams & Wilkins.