| Literature DB >> 1212023 |
F C Colpaert, C J Niemegeers, P A Janssen.
Abstract
Various non-narcotic drugs with intrinsic stimulus properties were found not to be generalized with fentanyl treatment in rats trained to discriminate fentanyl (0.04 mg/kg, s.c., t-30') from its solvent (s.c., t-30'). In contrast, five typical narcotic analgesics yielded dose-dependent generalization with fentanyl treatment. The results evidence the specific character of the narcotic cue in rats.Entities:
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Year: 1975 PMID： 1212023
Source DB: PubMed Journal: Arch Int Pharmacodyn Ther ISSN： 0003-9780