Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Watery diarrhoea and ganglioneuroma with secretion of vasoactive intestinal peptide.

Literature DB >> 1211964

Watery diarrhoea and ganglioneuroma with secretion of vasoactive intestinal peptide.

Abstract

A young girl presenting with diarrhoea and stridor was found to have a thoracic ganglioneuroma. The tumour, which was partially resected, contained an abnormally high amount of vasoactive intestinal peptide (VIP) as measured by radioimmunoassay. This decreased after the operation. In addition, analysis of urine showed the presence of abnormal amounts of catecholamines and catechol metabolites. The findings suggest that the diarrhoea in the syndrome of ganglioneuroma and bowel dysfunction is due to an excess of VIP secreted by the tumour.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Catecholamines
Peptides

Year: 1975 PMID： 1211964 PMCID： PMC1545737 DOI： 10.1136/adc.50.11.896

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

7 in total

1. DIARRHEA IN A CHILD WITH A CATECHOLAMINE-SECRETING GANGLIONEUROMA. CASE REPORT AND REVIEW OF THE LITERATUTE.

Authors: B J ROSENSTEIN; K ENGELMAN
Journal: J Pediatr Date: 1963-08 Impact factor: 4.406

2. Catecholamines and diarrhea in ganglioneuroblastoma.

Authors: G B STICKLER; G A HALLENBECK; E V FLOCK; J W ROSEVEAR
Journal: Am J Dis Child Date: 1962-12

3. Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia.

Authors: J V VERNER; A B MORRISON
Journal: Am J Med Date: 1958-09 Impact factor: 4.965

4. Secreting Intrathoracic Ganglioneuroma.

Authors: J M Smellie; M Sandler
Journal: Proc R Soc Med Date: 1961-04

5. Vasoactive intestinal peptide and watery-diarrhoea syndrome.

Authors: S R Bloom; J M Polak; A G Pearse
Journal: Lancet Date: 1973-07-07 Impact factor: 79.321

6. Prostaglandins in amine-peptide-secreting tumours.

Authors: M Sandler; S M Karim; E D Williams
Journal: Lancet Date: 1968-11-16 Impact factor: 79.321

7. Diarrhea associated with adrenal ganglioneuroma. New findings related to the pathogenesis of diarrhea.

Authors: J R Hamilton; I C Radde; G Johnson
Journal: Am J Med Date: 1968-03 Impact factor: 4.965

7 in total

11 in total

1. Vasoactive intestinal peptide, the major mediator of the WDHA (pancreatic cholera) syndrome: value of measurement in diagnosis and treatment.

Authors: S R Bloom
Journal: Am J Dig Dis Date: 1978-04

Review 2. Pathophysiology of gastrointestinal hormones. Implications for paediatrics.

Authors: I Henrichs; W M Teller
Journal: Eur J Pediatr Date: 1980-10 Impact factor: 3.183

Review 3. VIP secreting tumours in infancy. A review of radiological appearances.

Authors: R P Davies; J P Slavotinek; S F Dorney
Journal: Pediatr Radiol Date: 1990

4. Intractable diarrhoea in a patient with vasoactive intestinal peptide-secreting neuroblastoma. Attempted control by somatostatin.

Authors: K Tiedemann; J Pritchard; R Long; S R Bloom
Journal: Eur J Pediatr Date: 1981-10 Impact factor: 3.183

9. Watery diarrhoea and elevated vasoactive intestine polypeptide associated with a massive neurofibroma in early childhood.

Authors: D J Carson; J F Glasgow; J Ardill
Journal: J R Soc Med Date: 1980-01 Impact factor: 18.000

10. Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease.

Authors: Madhuri Badrinath; Rachana Mandru; Dhruv Lowe; Divey Manocha; Ted Achufusi
Journal: ACG Case Rep J Date: 2019-07-11