Literature DB >> 12119612

Moving smaller in drug discovery and delivery.

David A LaVan1, David M Lynn, Robert Langer.   

Abstract

Advances in new micro- and nanotechnologies are accelerating the identification and evaluation of drug candidates, and the development of new delivery technologies that are required to transform biological potential into medical reality. This article will highlight the emerging micro- and nanotechnology tools, techniques and devices that are being applied to advance the fields of drug discovery and drug delivery. Many of the promising applications of micro- and nanotechnology are likely to occur at the interfaces between microtechnology, nanotechnology and biochemistry.

Mesh:

Year:  2002        PMID: 12119612     DOI: 10.1038/nrd707

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  34 in total

1.  Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin.

Authors:  Stephen Soukasene; Daniel J Toft; Tyson J Moyer; Hsuming Lu; Hyung-Kun Lee; Stephany M Standley; Vincent L Cryns; Samuel I Stupp
Journal:  ACS Nano       Date:  2011-11-01       Impact factor: 15.881

2.  Nanoparticle-induced platelet aggregation and vascular thrombosis.

Authors:  Anna Radomski; Paul Jurasz; David Alonso-Escolano; Magdalena Drews; Maria Morandi; Tadeusz Malinski; Marek W Radomski
Journal:  Br J Pharmacol       Date:  2005-11       Impact factor: 8.739

Review 3.  What can nanotechnology do to fight cancer?

Authors:  Oscar Gallego; Víctor Puntes
Journal:  Clin Transl Oncol       Date:  2006-11       Impact factor: 3.405

4.  Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents.

Authors:  Glauco R Souza; Dawn R Christianson; Fernanda I Staquicini; Michael G Ozawa; Evan Y Snyder; Richard L Sidman; J Houston Miller; Wadih Arap; Renata Pasqualini
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-24       Impact factor: 11.205

5.  But is it unique to nanotechnology?: reframing nanoethics.

Authors:  Marion Godman
Journal:  Sci Eng Ethics       Date:  2008-02-12       Impact factor: 3.525

6.  Stimulation of single isolated adult ventricular myocytes within a low volume using a planar microelectrode array.

Authors:  Norbert Klauke; Godfrey L Smith; Jon Cooper
Journal:  Biophys J       Date:  2003-09       Impact factor: 4.033

7.  Role of particle size in phagocytosis of polymeric microspheres.

Authors:  Julie A Champion; Amanda Walker; Samir Mitragotri
Journal:  Pharm Res       Date:  2008-03-29       Impact factor: 4.200

8.  Luteolin nanoparticle in chemoprevention: in vitro and in vivo anticancer activity.

Authors:  Debatosh Majumdar; Kyung-Ho Jung; Hongzheng Zhang; Sreenivas Nannapaneni; Xu Wang; A R M Ruhul Amin; Zhengjia Chen; Zhuo G Chen; Dong M Shin
Journal:  Cancer Prev Res (Phila)       Date:  2014-01

9.  The architecture and biological performance of drug-loaded LbL nanoparticles.

Authors:  Stephen W Morton; Zhiyong Poon; Paula T Hammond
Journal:  Biomaterials       Date:  2013-04-22       Impact factor: 12.479

10.  Gold nanorods mediated controlled release of doxorubicin: nano-needles for efficient drug delivery.

Authors:  Sunil Pandey; Ritu Shah; Ashmi Mewada; Mukeshchand Thakur; Goldie Oza; Madhuri Sharon
Journal:  J Mater Sci Mater Med       Date:  2013-03-23       Impact factor: 3.896

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