| Literature DB >> 23526136 |
Sunil Pandey1, Ritu Shah, Ashmi Mewada, Mukeshchand Thakur, Goldie Oza, Madhuri Sharon.
Abstract
Use of cysteamine hydrochloride (Cys-HCl) protected gold nanorods (GNRs) as efficient carrier of widely used anti-cancer drug doxorubicin using folic acid as navigational molecule is presented in this work. GNRs were found to have excellent drug loading capacity of >97 %. A detailed comprehension of in vitro drug release profile under ideal physiological condition was found to obey 1st order kinetics at pH 6.8, 5.3 and 7.2, an ideal milieu for drug delivery to solid tumours.Entities:
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Year: 2013 PMID： 23526136 DOI： 10.1007/s10856-013-4915-4
Source DB: PubMed Journal: J Mater Sci Mater Med ISSN： 0957-4530 Impact factor: 3.896