Literature DB >> 12117297

Carcinogenic effects of polychlorinated biphenyls.

O M Faroon1, S Keith, D Jones, C De Rosa.   

Abstract

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of an important section of the Toxicological profile for polychlorinated biphenyls [ATSDR. 2000: Toxicological profile for polychlorinated biphenyls. Atlanta, GA: US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry.] into the scientific literature. This article focuses on the carcinogenic effects of this group of synthetic organic chemicals (polychlorinated biphenyls) in humans and animals. Information on other health effects, toxicokinetics, mechanisms of toxicity, biomarkers, interactions, chemical and physical properties, potential for human exposure, and regulations and advisories is detailed in the profile.

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Year:  2001        PMID： 12117297     DOI： 10.1191/0748233701th098oa

Source DB:  PubMed          Journal:  Toxicol Ind Health        ISSN： 0748-2337            Impact factor:   2.273


  22 in total

1.  3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats.

Authors:  J A Jacobus; B Wang; C Maddox; H Esch; L Lehmann; L W Robertson; K Wang; P Kirby; G Ludewig
Journal:  Environ Int       Date:  2010-08-23       Impact factor: 9.621

2.  Transcriptional profiling and biological pathway analysis of human equivalence PCB exposure in vitro: indicator of disease and disorder development in humans.

Authors:  Somiranjan Ghosh; Partha S Mitra; Christopher A Loffredo; Tomas Trnovec; Lubica Murinova; Eva Sovcikova; Svetlana Ghimbovschi; Shizhu Zang; Eric P Hoffman; Sisir K Dutta
Journal:  Environ Res       Date:  2015-02-27       Impact factor: 6.498

3.  Congener specific polychlorinated biphenyl metabolism by human intestinal microbe Clostridium species: Comparison with human liver cell line-HepG2.

Authors:  Supriyo De; Somiranjan Ghosh; Sisir K Dutta
Journal:  Indian J Microbiol       Date:  2006-09       Impact factor: 2.461

4.  PCB exposure and potential future cancer incidence in Slovak children: an assessment from molecular finger printing by Ingenuity Pathway Analysis (IPA®) derived from experimental and epidemiological investigations.

Authors:  Somiranjan Ghosh; Christopher A Loffredo; Partha S Mitra; Tomas Trnovec; Lubica Palkovicova Murinova; Eva Sovcikova; Eric P Hoffman; Kepher H Makambi; Sisir K Dutta
Journal:  Environ Sci Pollut Res Int       Date:  2017-11-15       Impact factor: 4.223

5.  Post-9/11 cancer incidence in World Trade Center-exposed New York City firefighters as compared to a pooled cohort of firefighters from San Francisco, Chicago and Philadelphia (9/11/2001-2009).

Authors:  William Moir; Rachel Zeig-Owens; Robert D Daniels; Charles B Hall; Mayris P Webber; Nadia Jaber; James H Yiin; Theresa Schwartz; Xiaoxue Liu; Madeline Vossbrinck; Kerry Kelly; David J Prezant
Journal:  Am J Ind Med       Date:  2016-09       Impact factor: 2.214

6.  Insight on the interaction of polychlorobiphenyl with nucleic acid-base.

Authors:  Soraya Abtouche; Thibaut Very; Antonio Monari; Meziane Brahimi; Xavier Assfeld
Journal:  J Mol Model       Date:  2012-09-13       Impact factor: 1.810

7.  Differential gene expression and a functional analysis of PCB-exposed children: understanding disease and disorder development.

Authors:  Sisir K Dutta; Partha S Mitra; Somiranjan Ghosh; Shizhu Zang; Dean Sonneborn; Irva Hertz-Picciotto; Tomas Trnovec; Lubica Palkovicova; Eva Sovcikova; Svetlana Ghimbovschi; Eric P Hoffman
Journal:  Environ Int       Date:  2011-09-08       Impact factor: 9.621

8.  Historical reconstruction of polychlorinated biphenyl (PCB) exposures for workers in a capacitor manufacturing plant.

Authors:  Nancy B Hopf; Avima M Ruder; Martha A Waters
Journal:  Environ Sci Pollut Res Int       Date:  2013-03-09       Impact factor: 4.223

9.  Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.

Authors:  Rui Wu; Albert S Reger; Jian Cao; Andrew M Gulick; Debra Dunaway-Mariano
Journal:  Biochemistry       Date:  2007-11-21       Impact factor: 3.162

10.  Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice.

Authors:  Howard P Glauert; Job C Tharappel; Subhashis Banerjee; Nelson L S Chan; Izabela Kania-Korwel; Hans-Joachim Lehmler; Eun Y Lee; Larry W Robertson; Brett T Spear
Journal:  Toxicol Appl Pharmacol       Date:  2008-07-02       Impact factor: 4.219
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