Literature DB >> 12112303

Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.).

Kenji Okazaki1, Kazuyoshi Kawazoe, Yoshihisa Takaishi.   

Abstract

Two antiaggregant compounds, thymol (compound 1) and 3,4,3',4'-tetrahydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme (Thymus vulgaris L.). The structures were determined by (1)H-, (13)C-NMR and mass spectra (MS) studies. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid (AA) and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin. Copyright 2002 John Wiley & Sons, Ltd.

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Year:  2002        PMID： 12112303     DOI： 10.1002/ptr.979

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  8 in total

1.  Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors:  Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
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Review 2.  Medicinal plants with antithrombotic property in Persian medicine: a mechanistic review.

Authors:  Zahra Memariani; Reihaneh Moeini; Shokooh Sadat Hamedi; Narjes Gorji; Seyyed Ali Mozaffarpur
Journal:  J Thromb Thrombolysis       Date:  2018-01       Impact factor: 2.300

Review 3.  Anti-coagulant activity of plants: mini review.

Authors:  Muhammad Akram; Abid Rashid
Journal:  J Thromb Thrombolysis       Date:  2017-10       Impact factor: 2.300

Review 4.  Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review.

Authors:  Cristina M Uritu; Cosmin T Mihai; Gabriela-Dumitrita Stanciu; Gianina Dodi; Teodora Alexa-Stratulat; Andrei Luca; Maria-Magdalena Leon-Constantin; Raluca Stefanescu; Veronica Bild; Silvia Melnic; Bogdan I Tamba
Journal:  Pain Res Manag       Date:  2018-05-08       Impact factor: 3.037

5.  Thymol Isolated from Thymus vulgaris L. Inhibits Colorectal Cancer Cell Growth and Metastasis by Suppressing the Wnt/β-Catenin Pathway.

Authors:  Qiongyao Zeng; Yuncheng Che; Yu Zhang; Mei Chen; Qiang Guo; Wenjing Zhang
Journal:  Drug Des Devel Ther       Date:  2020-07-01       Impact factor: 4.162

Review 6.  Evaluation of botanicals as potential COVID-19 symptoms terminator.

Authors:  Ufuk Koca Caliskan; Methiye Mancak Karakus
Journal:  World J Gastroenterol       Date:  2021-10-21       Impact factor: 5.374

7.  Correlation between the chemical composition and the antimicrobial properties of seven samples of essential oils of endemic Thymes in Morocco against multi-resistant bacteria and pathogenic fungi.

Authors:  Aziz Drioiche; Fatima Zahra Radi; Atika Ailli; Amal Bouzoubaa; Amale Boutakiout; Soumia Mekdad; Omkulthom Al Kamaly; Asmaa Saleh; Mohamed Maouloua; Dalila Bousta; Server Sahpaz; Fadoua El Makhoukhi; Touriya Zair
Journal:  Saudi Pharm J       Date:  2022-06-22       Impact factor: 4.562

8.  Plasma retinol-binding protein-4 and tumor necrosis factor-α are reduced in postmenopausal women after combination of different intensities of circuit resistance training and Zataria supplementation.

Authors:  Seyed Morteza Tayebi; Ayoub Saeidi; Mohamad Fashi; Seyed Pouya; Abedin Khosravi; Hossein Shirvani; Mehdi Ahmadian; Abderraouf Ben Abderrahman; Anthony C Hackney; Hassane Zouhal
Journal:  Sport Sci Health       Date:  2019-03-15
  8 in total

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