Literature DB >> 12106781

Genetic approaches to the study of Toll-like receptor function.

Osamu Takeuchi1, Shizuo Akira.   

Abstract

The Toll-like receptor (TLR) family plays a role in sensing invading pathogens. Ten members have been reported to date, seven of which were found to recognize discrete bacterial components. Mouse models lacking each TLR and its signaling molecule are useful tools for the analysis of the innate immune system.

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Year:  2002        PMID： 12106781     DOI： 10.1016/s1286-4579(02)01615-5

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  12 in total

1.  TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children.

Authors:  Afig Berdeli; Handan Ak Celik; Ruhi Ozyürek; Buket Dogrusoz; Hikmet Hakan Aydin
Journal:  J Mol Med (Berl)       Date:  2005-06-21       Impact factor: 4.599

2.  Macrophage activation: role of toll-like receptors, nitric oxide, and nuclear factor kappa B.

Authors:  Blase Billack
Journal:  Am J Pharm Educ       Date:  2006-10-15       Impact factor: 2.047

3.  Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters.

Authors:  Kavita J Rangan; Yu-Ying Yang; Guillaume Charron; Howard C Hang
Journal:  J Am Chem Soc       Date:  2010-08-11       Impact factor: 15.419

4.  The role of TLR2, TRL3, TRL4, and TRL9 signaling in the pathogenesis of autoimmune disease in a retinal autoimmunity model.

Authors:  Jiazhu Fang; Dan Fang; Phyllis B Silver; Feng Wen; Bing Li; Xiangrong Ren; Qing Lin; Rachel R Caspi; Shao Bo Su
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-01-27       Impact factor: 4.799

5.  Characteristic Immune Response in Peyer's Patch Cells Induced by Oral Administration of Bifidobacterium Components.

Authors:  Yusuke Nakanishi; Akira Hosono; Yasuhiro Hiramatsu; Teiji Kimura; Ryo Nakamura; Shuichi Kaminogawa
Journal:  Cytotechnology       Date:  2005-01       Impact factor: 2.058

6.  Early induction of interferon-responsive mRNAs in Creutzfeldt-Jakob disease.

Authors:  Christopher A Baker; Zhi Yun Lu; Laura Manuelidis
Journal:  J Neurovirol       Date:  2004-02       Impact factor: 2.643

7.  TLR2 expression in relation to IL-6 and IL-1beta and their natural regulators production by PMN and PBMC in patients with Lyme disease.

Authors:  Ewa Jablonska; Magdalena Marcinczyk
Journal:  Mediators Inflamm       Date:  2006       Impact factor: 4.711

Review 8.  Toll-like receptor downstream signaling.

Authors:  Taro Kawai; Shizuo Akira
Journal:  Arthritis Res Ther       Date:  2004-11-30       Impact factor: 5.156

9.  Molecular characterization and analysis of TLR-1 in rabbit tissues.

Authors:  Wael M K Elfeil; Abdelazeem M Algammal; Reham R Abouelmaatti; Ahmed Gerdouh; Mohamed Abdeldaim
Journal:  Cent Eur J Immunol       Date:  2016-10-25       Impact factor: 2.085

10.  Protective role of MyD88-independent innate immune responses against prion infection.

Authors:  Daisuke Ishibashi; Ryuichiro Atarashi; Noriyuki Nishida
Journal:  Prion       Date:  2012-10-23       Impact factor: 3.931
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