Literature DB >> 12101453

The role of the posterior ciliary body in the biosynthesis of vitreous humour.

P N Bishop1, M Takanosu, M Le Goff, R Mayne.   

Abstract

Recently, several groups have published new information regarding the origins and structure of the vitreous humour, and the inner limiting lamina (ILL) of the retina. This short article provides an overview of this new information. It is proposed that vitreous proteins are derived from several different cell types with the posterior half of the non-pigmented ciliary epithelium being prominent in the expression of several connective tissue macromolecules. In addition, some basement membrane macromolecules are also expressed by the ciliary body and may subsequently be assembled on the surface of the Müller cells to form the ILL. New data suggest that the posterior half of the non-pigmented ciliary epithelium has substantial secretory activity and is likely to play a pivotal role in eye development.

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Year:  2002        PMID: 12101453     DOI: 10.1038/sj.eye.6700199

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  25 in total

1.  Immunolocalisation of opticin in the human eye.

Authors:  S Ramesh; R E Bonshek; P N Bishop
Journal:  Br J Ophthalmol       Date:  2004-05       Impact factor: 4.638

2.  Vitreous collagen metabolism before and after vitrectomy.

Authors:  Hirotaka Itakura; Shoji Kishi; Nobuo Kotajima; Masami Murakami
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-10-20       Impact factor: 3.117

Review 3.  Cochlin and glaucoma: a mini-review.

Authors:  Sanjoy K Bhattacharya; Neal S Peachey; John W Crabb
Journal:  Vis Neurosci       Date:  2005 Sep-Oct       Impact factor: 3.241

4.  The vitreous glycoprotein opticin inhibits preretinal neovascularization.

Authors:  Magali M Le Goff; Hongbin Lu; Marta Ugarte; Stephen Henry; Masamine Takanosu; Richard Mayne; Paul N Bishop
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-01-25       Impact factor: 4.799

5.  Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression.

Authors:  David C Assheton; Eoin P Guerin; Carl M Sheridan; Paul N Bishop; Paul S Hiscott
Journal:  Br J Ophthalmol       Date:  2006-09-27       Impact factor: 4.638

6.  Spatial and temporal dissociation of AQP4 and Kir4.1 expression during induction of refractive errors.

Authors:  Melinda J Goodyear; Sheila G Crewther; Melanie J Murphy; Loretta Giummarra; Agnes Hazi; Barbara M Junghans; David P Crewther
Journal:  Mol Vis       Date:  2010-08-14       Impact factor: 2.367

7.  Analysis of the vitreous membrane in a case of type 1 Stickler syndrome.

Authors:  Tadashi Yokoi; Ryouhei Koide; Kentaro Matsuoka; Atsuko Nakagawa; Noriyuki Azuma
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-12-17       Impact factor: 3.117

8.  Human retinal pigment epithelium proteome changes in early diabetes.

Authors:  A Decanini; P R Karunadharma; C L Nordgaard; X Feng; T W Olsen; D A Ferrington
Journal:  Diabetologia       Date:  2008-04-15       Impact factor: 10.122

9.  Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-beta1.

Authors:  Florian Sommer; Klaus Pollinger; Ferdinand Brandl; Barbara Weiser; Jörg Tessmar; Torsten Blunk; Achim Göpferich
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-05-07       Impact factor: 3.117

10.  Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera.

Authors:  Tiarnan D L Keenan; Simon J Clark; Richard D Unwin; Liam A Ridge; Anthony J Day; Paul N Bishop
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-11-07       Impact factor: 4.799

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