Literature DB >> 12098723

A multicentre observational study of presentation and early assessment of acute stroke.

Farzaneh Harraf1, Anil K Sharma, Martin M Brown, Kennedy R Lees, Richard I Vass, Lalit Kalra.   

Abstract

OBJECTIVE: To investigate delays in the presentation to hospital and evaluation of patients with suspected stroke.
DESIGN: Multicentre prospective observational study.
SETTING: 22 hospitals in the United Kingdom and Dublin. PARTICIPANTS: 739 patients with suspected stroke presenting to hospital. MAIN OUTCOME MEASURES: Time from onset of stroke symptoms to arrival at hospital, and time from arrival to evaluation by a senior doctor.
RESULTS: The median age of patients was 75 years, and 400 were women. The median delay between onset of symptoms and arrival at hospital was 6 hours (interquartile range 1 hour 48 minutes to 19 hours 12 minutes). 37% of patients arrived within 3 hours, 50% within 6 hours. The median delay for patients using the emergency service was 2 hours 3 minutes (47 minutes to 7 hours 12 minutes) compared with 7 hours 12 minutes (2 hours 5 minutes to 20 hours 37 minutes) for referrals from general practitioners (P<0.0001). Use of emergency services reduced delays to hospital (odds ratio 0.45, 95% confidence interval 0.23 to 0.61). The median time to evaluation by a senior doctor was 1 hour 9 minutes (interquartile range 33 minutes to 1 hour 50 minutes) but was undertaken in only 477 (65%) patients within 3 hours of arrival. This was not influenced by age, sex, time of presentation, mode of referral, hospital type, or the presence of a stroke unit. Computed tomography was requested within 3 hours of arrival in 166 (22%) patients but undertaken in only 60 (8%).
CONCLUSION: Delays in patients arriving at hospital with suspected stroke can be reduced by the increased use of emergency services. Over a third of patients arrive at hospital within three hours of stroke; their management can be improved by expediting medical evaluation and performing computed tomography early.

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Mesh:

Year:  2002        PMID: 12098723      PMCID: PMC116666          DOI: 10.1136/bmj.325.7354.17

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  21 in total

1.  Acute stroke therapy at the millennium: consummating the marriage between the laboratory and bedside. The Feinberg lecture.

Authors:  J C Grotta
Journal:  Stroke       Date:  1999-08       Impact factor: 7.914

2.  ABC of arterial and venous disease. Acute stroke.

Authors:  P M Bath; K R Lees
Journal:  BMJ       Date:  2000-04-01

3.  A late step in the right direction of stroke care.

Authors:  W Hacke
Journal:  Lancet       Date:  2000-09-09       Impact factor: 79.321

Review 4.  Prehospital and in-hospital delays in acute stroke care.

Authors:  K R Evenson; W D Rosamond; D L Morris
Journal:  Neuroepidemiology       Date:  2001-05       Impact factor: 3.282

Review 5.  Thrombolysis.

Authors:  K R Lees
Journal:  Br Med Bull       Date:  2000       Impact factor: 4.291

Review 6.  Treatment and secondary prevention of stroke: evidence, costs, and effects on individuals and populations.

Authors:  G J Hankey; C P Warlow
Journal:  Lancet       Date:  1999-10-23       Impact factor: 79.321

7.  Delay in presentation and evaluation for acute stroke: Stroke Time Registry for Outcomes Knowledge and Epidemiology (S.T.R.O.K.E.).

Authors:  C R Lacy; D C Suh; M Bueno; J B Kostis
Journal:  Stroke       Date:  2001-01       Impact factor: 7.914

8.  Determinants of use of emergency medical services in a population with stroke symptoms: the Second Delay in Accessing Stroke Healthcare (DASH II) Study.

Authors:  E B Schroeder; W D Rosamond; D L Morris; K R Evenson; A R Hinn
Journal:  Stroke       Date:  2000-11       Impact factor: 7.914

9.  Prehospital and emergency department delays after acute stroke: the Genentech Stroke Presentation Survey.

Authors:  D L Morris; W Rosamond; K Madden; C Schultz; S Hamilton
Journal:  Stroke       Date:  2000-11       Impact factor: 7.914

Review 10.  Recommendations for the establishment of primary stroke centers. Brain Attack Coalition.

Authors:  M J Alberts; G Hademenos; R E Latchaw; A Jagoda; J R Marler; M R Mayberg; R D Starke; H W Todd; K M Viste; M Girgus; T Shephard; M Emr; P Shwayder; M D Walker
Journal:  JAMA       Date:  2000-06-21       Impact factor: 56.272

View more
  40 in total

1.  Barriers to effective stroke care out of hours need to be broached.

Authors:  Mark F Nicol
Journal:  BMJ       Date:  2002-09-14

2.  [Recommendations of the European Stroke Initiative (EUSI) for treatment of ischemic stroke--update 2003. I. organization and acute therapy].

Authors:  Sonja Külkens; Peter Arthur Ringleb; Werner Hacke
Journal:  Nervenarzt       Date:  2004-04       Impact factor: 1.214

3.  [Concept for allocation of acute stroke patients: evaluation of the quality of diagnosis reached by the emergency medical services of Münster].

Authors:  M Schilling; M Kros; M Ritter; M Ohms; W R Schäbitz; W Kusch; E B Ringelstein; T P Weber; U Harding; A Bohn
Journal:  Nervenarzt       Date:  2012-06       Impact factor: 1.214

4.  Patient delay in acute stroke response.

Authors:  T Hemmen
Journal:  Eur J Neurol       Date:  2008-04       Impact factor: 6.089

5.  [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1].

Authors:  P Ringleb; P D Schellinger; W Hacke
Journal:  Nervenarzt       Date:  2008-08       Impact factor: 1.214

6.  Delay in presentation after acute ischemic stroke: the Careggi Hospital Stroke Registry.

Authors:  Innocenti Eleonora; Nencini Patrizia; Romani Ilaria; Del Bene Alessandra; Arba Francesco; Piccardi Benedetta; Pracucci Giovanni
Journal:  Neurol Sci       Date:  2013-06-27       Impact factor: 3.307

7.  Prehospital notification by emergency medical services reduces delays in stroke evaluation: findings from the North Carolina stroke care collaborative.

Authors:  Mehul D Patel; Kathryn M Rose; Emily C O'Brien; Wayne D Rosamond
Journal:  Stroke       Date:  2011-06-09       Impact factor: 7.914

Review 8.  Organization of regional and local stroke resources: methods to expedite acute management of stroke.

Authors:  James Kennedy; Christina Ma; Alastair M Buchan
Journal:  Curr Neurol Neurosci Rep       Date:  2004-01       Impact factor: 5.081

Review 9.  Early identification and delay to treatment in myocardial infarction and stroke: differences and similarities.

Authors:  Johan Herlitz; Birgitta Wireklintsundström; Angela Bång; Annika Berglund; Leif Svensson; Christian Blomstrand
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2010-09-06       Impact factor: 2.953

10.  Influence of direct admission to Comprehensive Stroke Centers on the outcome of acute stroke patients treated with intravenous thrombolysis.

Authors:  Natalia Pérez de la Ossa; Mónica Millán; Juan F Arenillas; Josep Sánchez-Ojanguren; Ernest Palomeras; Laura Dorado; Cristina Guerrero; Antoni Dávalos
Journal:  J Neurol       Date:  2009-04-08       Impact factor: 4.849

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