| Literature DB >> 12098233 |
Dennis J Hurley1, Susan E Seaman, Jan C Mazura, Yitzhak Tor.
Abstract
[structure: see text] A fluorescent deoxyuridine analogue is sensitive to the polarity of its environment and exhibits a distinct emission profile in single- vs double-stranded oligonucleotides. Emission-monitored denaturation curves of internally modified dU(phen) duplexes are characteristic of the base opposite dU(phen) and distinguish between perfect and mismatched complementary oligonucleotides.Entities:
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Year: 2002 PMID： 12098233 DOI： 10.1021/ol026043x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005