Literature DB >> 12097603

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains two functional lytic origins of DNA replication.

David P AuCoin1, Kelly S Colletti, Yiyang Xu, Sylvia A Cei, Gregory S Pari.   

Abstract

We used a transient-transfection replication assay to identify two functional copies of the human herpesvirus 8 (HHV8) lytic origin of DNA replication (oriLyt). BCLB-1 cells were transfected with HHV8 subgenomic fragments containing the putative lytic origin along with a plasmid expressing viral transactivator open reading frame (ORF) 50. The HHV8 left-end oriLyt (oriLyt-L) lies between ORFs K4.2 and K5 and is composed of a region encoding various transcription factor binding sites and an A+T-rich region and a G+C repeat region. The right-end oriLyt (oriLyt-R) maps between ORF 69 and vFLIP, a region similar to the RRV oriLyt, and is an inverted duplication of oriLyt-L.

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Year:  2002        PMID： 12097603      PMCID： PMC136389          DOI： 10.1128/jvi.76.15.7890-7896.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  36 in total

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Authors:  D M Lukac; L Garibyan; J R Kirshner; D Palmeri; D Ganem
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2.  The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters.

Authors:  S Kenney; J Kamine; E Holley-Guthrie; J C Lin; E C Mar; J Pagano
Journal:  J Virol       Date:  1989-04       Impact factor: 5.103

3.  Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus.

Authors:  W Hammerschmidt; B Sugden
Journal:  Cell       Date:  1988-11-04       Impact factor: 41.582

4.  Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

Authors:  J Countryman; G Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

5.  Identification of a cellular protein that interacts and synergizes with the RTA (ORF50) protein of Kaposi's sarcoma-associated herpesvirus in transcriptional activation.

Authors:  S Wang; S Liu; M H Wu; Y Geng; C Wood
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

6.  Human-herpesvirus-8-encoded K8 protein colocalizes with the promyelocytic leukemia protein (PML) bodies and recruits p53 to the PML bodies.

Authors:  H Katano; K Ogawa-Goto; H Hasegawa; T Kurata; T Sata
Journal:  Virology       Date:  2001-08-01       Impact factor: 3.616

7.  Stable DNA unwinding, not "breathing," accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences.

Authors:  D Kowalski; D A Natale; M J Eddy
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

8.  In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.

Authors:  E Cesarman; P S Moore; P H Rao; G Inghirami; D M Knowles; Y Chang
Journal:  Blood       Date:  1995-10-01       Impact factor: 22.113

9.  Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter.

Authors:  A Chevallier-Greco; E Manet; P Chavrier; C Mosnier; J Daillie; A Sergeant
Journal:  EMBO J       Date:  1986-12-01       Impact factor: 11.598

10.  The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication origin.

Authors:  D Kowalski; M J Eddy
Journal:  EMBO J       Date:  1989-12-20       Impact factor: 11.598
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  42 in total

1.  Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: cis-acting requirements for replication and ori-Lyt-associated RNA transcription.

Authors:  Yan Wang; Hong Li; Man Yee Chan; Fan Xiu Zhu; David M Lukac; Yan Yuan
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

2.  Evidence for DNA hairpin recognition by Zta at the Epstein-Barr virus origin of lytic replication.

Authors:  Andrew J Rennekamp; Pu Wang; Paul M Lieberman
Journal:  J Virol       Date:  2010-05-05       Impact factor: 5.103

3.  Evaluation of the lytic origins of replication of Kaposi's sarcoma-associated virus/human herpesvirus 8 in the context of the viral genome.

Authors:  Yiyang Xu; Alicia Rodriguez-Huete; Gregory S Pari
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

4.  Transcriptional analysis of latent and inducible Kaposi's sarcoma-associated herpesvirus transcripts in the K4 to K7 region.

Authors:  Jennifer L Taylor; Heather N Bennett; Beth A Snyder; Patrick S Moore; Yuan Chang
Journal:  J Virol       Date:  2005-12       Impact factor: 5.103

5.  Investigation of the multimerization region of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) protein K-bZIP: the proposed leucine zipper region encodes a multimerization domain with an unusual structure.

Authors:  Salama Al Mehairi; Eleanora Cerasoli; Alison J Sinclair
Journal:  J Virol       Date:  2005-06       Impact factor: 5.103

6.  Promoter- and cell-specific transcriptional transactivation by the Kaposi's sarcoma-associated herpesvirus ORF57/Mta protein.

Authors:  Diana Palmeri; Sophia Spadavecchia; Kyla Driscoll Carroll; David M Lukac
Journal:  J Virol       Date:  2007-10-03       Impact factor: 5.103

7.  The M10 locus of murine gammaherpesvirus 68 contributes to both the lytic and the latent phases of infection.

Authors:  B Flach; B Steer; N N Thakur; J Haas; H Adler
Journal:  J Virol       Date:  2009-06-03       Impact factor: 5.103

8.  Genome-wide identification of binding sites for Kaposi's sarcoma-associated herpesvirus lytic switch protein, RTA.

Authors:  Jiguo Chen; Fengchun Ye; Jianping Xie; Kurt Kuhne; Shou-Jiang Gao
Journal:  Virology       Date:  2009-02-23       Impact factor: 3.616

9.  Poly(ADP-ribose) polymerase 1 binds to Kaposi's sarcoma-associated herpesvirus (KSHV) terminal repeat sequence and modulates KSHV replication in latency.

Authors:  Eriko Ohsaki; Keiji Ueda; Shuhei Sakakibara; Eunju Do; Kaori Yada; Koichi Yamanishi
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10.  Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus 68.

Authors:  Danyang Gong; Jing Qi; Vaithilingaraja Arumugaswami; Ren Sun; Hongyu Deng
Journal:  Virology       Date:  2009-03-12       Impact factor: 3.616
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