| Literature DB >> 2987963 |
Abstract
We previously found that a form of Epstein-Barr virus with rearranged DNA induces replication of latent Epstein-Barr virus. We now have found that one of three fragments of this rearranged DNA, when cloned in recombinant plasmids and used to transfect cells, can activate expression of several polypeptides from a latent viral genome. The 33-kDa protein that is the product of the active fragment is likely to be responsible for disruption of latency.Entities:
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Year: 1985 PMID: 2987963 PMCID: PMC397939 DOI: 10.1073/pnas.82.12.4085
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205