Literature DB >> 1209652

Removal of manganese by chelating agents from brain and liver of manganese treated rats: as in vitro and an in vivo study.

S K Tandon, J Singh.   

Abstract

Some chelating agents were examined for their ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate. Nitrilotriacetic acid (NTA), 1,2-cyclohexylenedinitrilotetraacetic acid (CDTA) and diethylenetriaminepentaacetic acid (DTPA) were extremely effective in vivo while CDTA and p-aminosalicylic acid (PAS) were efficient in vitro.

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Year:  1975        PMID： 1209652     DOI： 10.1016/0300-483x(75)90120-1

Source DB:  PubMed          Journal:  Toxicology        ISSN： 0300-483X            Impact factor:   4.221


  6 in total

1.  In vitro inhibition of three phosphatases by mercuric chloride and their reversal by chelating agent EDTA.

Authors:  K V Sastry; K Sharma
Journal:  Bull Environ Contam Toxicol       Date:  1979-12       Impact factor: 2.151

2.  Chelation in metal intoxication. XII. Antidotal efficacy of chelating agents on acute toxicity of manganese.

Authors:  S K Tandon; S Khandelwal
Journal:  Arch Toxicol       Date:  1982-05       Impact factor: 5.153

3.  Neurochemical and biotransformational enzyme responses to manganese exposure in rats.

Authors:  E Hietanen; J Kilpiö; H Savolainen
Journal:  Arch Environ Contam Toxicol       Date:  1981       Impact factor: 2.804

4.  Chelation therapy of manganese intoxication with para-aminosalicylic acid (PAS) in Sprague-Dawley rats.

Authors:  Wei Zheng; Yue-Ming Jiang; Yanshu Zhang; Wendy Jiang; Xueqian Wang; Dallas M Cowan
Journal:  Neurotoxicology       Date:  2008-12-25       Impact factor: 4.294

5.  Sodium p-Aminosalicylic Acid Reverses Sub-Chronic Manganese-Induced Impairments of Spatial Learning and Memory Abilities in Rats, but Fails to Restore γ-Aminobutyric Acid Levels.

Authors:  Shao-Jun Li; Chao-Yan Ou; Sheng-Nan He; Xiao-Wei Huang; Hai-Lan Luo; Hao-Yang Meng; Guo-Dong Lu; Yue-Ming Jiang; Tanara Vieira Peres; Yi-Ni Luo; Xiang-Fa Deng
Journal:  Int J Environ Res Public Health       Date:  2017-04-10       Impact factor: 3.390

6.  Zinc is a novel intracellular second messenger.

Authors:  Satoru Yamasaki; Kumiko Sakata-Sogawa; Aiko Hasegawa; Tomoyuki Suzuki; Koki Kabu; Emi Sato; Tomohiro Kurosaki; Susumu Yamashita; Makio Tokunaga; Keigo Nishida; Toshio Hirano
Journal:  J Cell Biol       Date:  2007-05-14       Impact factor: 10.539
  6 in total

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