Literature DB >> 120936

Properties of [3H]taurine release from crude synaptosomal fractions of rat cerebral cortex.

P Placheta, E Singer, W Sieghart, M Karobath.   

Abstract

The release of previously accumulated [3H]taurine and [14C]GABA from crude synaptosomal (P2) fractions isolated from rat cerebral cortex was studied using a superfusion system. The spontaneous efflux of [3H]taurine and [14C]GABA was stimulated by elevated concentrations of K+ (15--133 mM) in a concentration-dependent manner. This K+-stimulated relase of [14C]Gaba but not of [3H]taurine was enhanced in the presence of Ca2+. However, addition of 3 mM Ca2+ to the superfusion medium in the presence of the ionophore A 23187 resulted in a stimulation of the release of both [3H]taurine and [14C]GABA. These results are discussed in connection with the cellular localization of taurine in the central nervous system.

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Year:  1979        PMID： 120936     DOI： 10.1007/bf00964467

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  41 in total

1.  Uptake of taurine into subcellular fractions of C-6 glioma cells.

Authors:  W Sieghart; M Karobath
Journal:  J Neurochem       Date:  1976-05       Impact factor: 5.372

2.  Nerve impulse-enhanced release of amino acids from non-synaptic regions of peripheral and central nerve trunks of bullfrog.

Authors:  D Weinreich; R Hammerschlag
Journal:  Brain Res       Date:  1975-01-24       Impact factor: 3.252

3.  The release of endogenous amino acids from the rat visual cortex.

Authors:  R M Clark; G G Collins
Journal:  J Physiol       Date:  1976-11       Impact factor: 5.182

4.  Efflux of amino acid neurotransmitters from rat spinal cord slices. II. Factors influencing the electrically induced efflux of ( 14 C)glycine and 3 H-GABA.

Authors:  J P Hammerstad; J E Murray; R W Cutler
Journal:  Brain Res       Date:  1971-12-24       Impact factor: 3.252

5.  Light stimulated release of [35 S]Taurine from chicken retina.

Authors:  H Pasantes-Morales; P F Urban; J Klethi; P Mandel
Journal:  Brain Res       Date:  1973-03-15       Impact factor: 3.252

6.  Sodium dependence of taurine uptake in rat brain synaptosomes.

Authors:  P Kontro; S S Oja
Journal:  Neuroscience       Date:  1978       Impact factor: 3.590

7.  A simple apparatus for studying the release of neurotransmitters from synaptosomes.

Authors:  M Raiteri; F Angelini; G Levi
Journal:  Eur J Pharmacol       Date:  1974-03       Impact factor: 4.432

8.  On the role of glial cells in the mammalian nervous system. Uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells.

Authors:  B K Schrier; E J Thompson
Journal:  J Biol Chem       Date:  1974-03-25       Impact factor: 5.157

9.  Calcium-dependent norepinephrine release from presynaptic nerve endings in vitro.

Authors:  M P Blaustein; E M Johnson; P Needleman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-08       Impact factor: 11.205

10.  Effects of selective doses of x-irradiation on the levels of several amino acids in the cerebellum of the rat.

Authors:  W J McBride; N S Nadi; J Altman; M H Aprison
Journal:  Neurochem Res       Date:  1976-04       Impact factor: 3.996
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  4 in total

1.  K+-evoked taurine efflux from cerebellar astrocytes: on the roles of Ca2+ and Na+.

Authors:  R A Philibert; K L Rogers; G R Dutton
Journal:  Neurochem Res       Date:  1989-01       Impact factor: 3.996

2.  Brain taurine content as a function of cerebral metabolic rate: osmotic regulation of glucose derived water production.

Authors:  N M van Gelder
Journal:  Neurochem Res       Date:  1989-06       Impact factor: 3.996

3.  Release of preloaded taurine and hypotaurine from astrocytes in primary culture: stimulation by calcium-free media.

Authors:  I Holopainen; P Kontro; S S Oja
Journal:  Neurochem Res       Date:  1985-01       Impact factor: 3.996

4.  Chloride dependence of the K(+)-stimulated release of taurine from synaptosomes.

Authors:  R Sánchez Olea; H Pasantes-Morales
Journal:  Neurochem Res       Date:  1990-05       Impact factor: 3.996
  4 in total

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