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Literature DB >> 12089113

The meningococcus tamed?

Abstract

Serogroup B Neisseria meningitidis is a frequent cause of invasive meningococcal disease, yet there are no effective vaccines suitable for routine immunisation. Limited efficacy has been shown with meningococcal outer membrane vacccines in children 4 years and older. Here we review the status of current research and consider new approaches to development of meningococcal serogroup B vaccines.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2002 PMID： 12089113 PMCID： PMC1751158 DOI： 10.1136/adc.87.1.13

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

56 in total

1. Epidemic serogroup B meningococcal disease in Oregon: the evolving epidemiology of the ET-5 strain.

Authors: M Diermayer; K Hedberg; F Hoesly; M Fischer; B Perkins; M Reeves; D Fleming
Journal: JAMA Date: 1999-04-28 Impact factor: 56.272

2. Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile.

Authors: J W Tappero; R Lagos; A M Ballesteros; B Plikaytis; D Williams; J Dykes; L L Gheesling; G M Carlone; E A Høiby; J Holst; H Nøkleby; E Rosenqvist; G Sierra; C Campa; F Sotolongo; J Vega; J Garcia; P Herrera; J T Poolman; B A Perkins
Journal: JAMA Date: 1999-04-28 Impact factor: 56.272

3. Bactericidal and cross-protective activities of a monoclonal antibody directed against Neisseria meningitidis NspA outer membrane protein.

Authors: N Cadieux; M Plante; C R Rioux; J Hamel; B R Brodeur; D Martin
Journal: Infect Immun Date: 1999-09 Impact factor: 3.441

4. Ferric enterobactin binding and utilization by Neisseria gonorrhoeae.

Authors: S D Carson; P E Klebba; S M Newton; P F Sparling
Journal: J Bacteriol Date: 1999-05 Impact factor: 3.490

5. Analysis of the human Ig isotype response to lactoferrin binding protein A from Neisseria meningitidis.

Authors: A S Johnson; A R Gorringe; F G Mackinnon; A J Fox; R Borrow; A Robinson
Journal: FEMS Immunol Med Microbiol Date: 1999-09

6. Household crowding a major risk factor for epidemic meningococcal disease in Auckland children.

Authors: M Baker; A McNicholas; N Garrett; N Jones; J Stewart; V Koberstein; D Lennon
Journal: Pediatr Infect Dis J Date: 2000-10 Impact factor: 2.129

7. Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins.

Authors: K Cartwright; R Morris; H Rümke; A Fox; R Borrow; N Begg; P Richmond; J Poolman
Journal: Vaccine Date: 1999-06-04 Impact factor: 3.641

8. Functional genomics of Neisseria meningitidis pathogenesis.

Authors: Y H Sun; S Bakshi; R Chalmers; C M Tang
Journal: Nat Med Date: 2000-11 Impact factor: 53.440

9. Allelic diversity of the two transferrin binding protein B gene isotypes among a collection of Neisseria meningitidis strains representative of serogroup B disease: implication for the composition of a recombinant TbpB-based vaccine.

Authors: B Rokbi; G Renauld-Mongenie; M Mignon; B Danve; D Poncet; C Chabanel; D A Caugant; M J Quentin-Millet
Journal: Infect Immun Date: 2000-09 Impact factor: 3.441

10. Conservation and accessibility of an inner core lipopolysaccharide epitope of Neisseria meningitidis.

Authors: J S Plested; K Makepeace; M P Jennings; M A Gidney; S Lacelle; J Brisson; A D Cox; A Martin; A G Bird; C M Tang; F M Mackinnon; J C Richards; E R Moxon
Journal: Infect Immun Date: 1999-10 Impact factor: 3.441

6 in total

1. Development, characterization, and functional activity of a panel of specific monoclonal antibodies to inner core lipopolysaccharide epitopes in Neisseria meningitidis.

Authors: Margaret Anne J Gidney; Joyce S Plested; Suzanne Lacelle; Philip A Coull; J Claire Wright; Katherine Makepeace; Jean-Robert Brisson; Andrew D Cox; E Richard Moxon; James C Richards
Journal: Infect Immun Date: 2004-01 Impact factor: 3.441

2. The incidence and mortality for meningococcal disease associated with area deprivation: an ecological study of hospital episode statistics.

Authors: R S Heyderman; Y Ben-Shlomo; C A Brennan; M Somerset
Journal: Arch Dis Child Date: 2004-11 Impact factor: 3.791

3. Llama single-chain antibody that blocks lipopolysaccharide binding and signaling: prospects for therapeutic applications.

Authors: Mohamed El Khattabi; Hendrik Adams; Erik Heezius; Pim Hermans; Frank Detmers; Bram Maassen; Peter van der Ley; Jan Tommassen; Theo Verrips; Jord Stam
Journal: Clin Vaccine Immunol Date: 2006-08-23