Literature DB >> 12818909

Treatment of meningococcal infection.

S B Welch1, S Nadel.   

Abstract

Aggressive early treatment of meningococcal disease can reduce mortality. This relies on prompt recognition and treatment of the complications of septicaemia and meningitis, appropriate ongoing intensive care where necessary, and adequate management of multiple organ failure. Most children with meningococcal disease survive intact, but long term sequelae are increasingly recognised and make follow up essential. New treatments continue to be evaluated, but none has so far proven to be effective in further reducing morbidity or mortality. Simple, timely therapeutic manoeuvres may greatly improve the prospects for survival.

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Year:  2003        PMID: 12818909      PMCID: PMC1763151          DOI: 10.1136/adc.88.7.608

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  35 in total

1.  The management of fever and petechiae: making sense of rash decisions.

Authors:  P A Brogan; A Raffles
Journal:  Arch Dis Child       Date:  2000-12       Impact factor: 3.791

Review 2.  Non-traumatic coma in children.

Authors:  F J Kirkham
Journal:  Arch Dis Child       Date:  2001-10       Impact factor: 3.791

3.  Mortality in severe meningococcal disease.

Authors:  K Thorburn; P Baines; A Thomson; C A Hart
Journal:  Arch Dis Child       Date:  2001-11       Impact factor: 3.791

4.  Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery.

Authors:  R Booy; P Habibi; S Nadel; C de Munter; J Britto; A Morrison; M Levin
Journal:  Arch Dis Child       Date:  2001-11       Impact factor: 3.791

5.  Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease.

Authors:  J B van Woensel; M H Biezeveld; A M Alders; A J Eerenberg; E Endert; E C Hack; I A von Rosenstiel; T W Kuijpers
Journal:  J Infect Dis       Date:  2001-12-03       Impact factor: 5.226

6.  Dysfunction of endothelial protein C activation in severe meningococcal sepsis.

Authors:  S N Faust; M Levin; O B Harrison; R D Goldin; M S Lockhart; S Kondaveeti; Z Laszik; C T Esmon; R S Heyderman
Journal:  N Engl J Med       Date:  2001-08-09       Impact factor: 91.245

7.  Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group.

Authors:  M Levin; P A Quint; B Goldstein; P Barton; J S Bradley; S D Shemie; T Yeh; S S Kim; D P Cafaro; P J Scannon; B P Giroir
Journal:  Lancet       Date:  2000-09-16       Impact factor: 79.321

8.  Neurodevelopmental outcome in meningococcal disease: a case-control study.

Authors:  J M Fellick; J A Sills; O Marzouk; C A Hart; R W Cooke; A P Thomson
Journal:  Arch Dis Child       Date:  2001-07       Impact factor: 3.791

9.  The orthopaedic management of peripheral ischaemia in meningococcal septicaemia in children.

Authors:  M S Davies; S Nadel; P Habibi; M Levin; D M Hunt
Journal:  J Bone Joint Surg Br       Date:  2000-04

10.  Investigation for complement deficiency following meningococcal disease.

Authors:  S Hoare; O El-Shazali; J E Clark; A Fay; A J Cant
Journal:  Arch Dis Child       Date:  2002-03       Impact factor: 3.791

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  8 in total

Review 1.  Pathophysiology of meningococcal meningitis and septicaemia.

Authors:  N Pathan; S N Faust; M Levin
Journal:  Arch Dis Child       Date:  2003-07       Impact factor: 3.791

2.  Persistently low plasma thioredoxin is associated with meningococcal septic shock in children.

Authors:  Matthew E Callister; Anne Burke-Gaffney; Gregory J Quinlan; Helen Betts; Simon Nadel; Timothy W Evans
Journal:  Intensive Care Med       Date:  2006-11-18       Impact factor: 17.440

3.  Meningitis is a common cause of convulsive status epilepticus with fever.

Authors:  R F M Chin; B G R Neville; R C Scott
Journal:  Arch Dis Child       Date:  2005-01       Impact factor: 3.791

4.  Mild meningococcaemia, pyrexia protocols and a problematic public health response.

Authors:  Luke Nelson Allen
Journal:  BMJ Case Rep       Date:  2014-05-07

Review 5.  Meningococcal vaccines.

Authors:  Jens U Rüggeberg; Andrew J Pollard
Journal:  Paediatr Drugs       Date:  2004       Impact factor: 3.022

Review 6.  Invasive Meningococcal Disease in the Vaccine Era.

Authors:  Simon Nadel; Nelly Ninis
Journal:  Front Pediatr       Date:  2018-11-09       Impact factor: 3.418

7.  Invasive meningococcal infection: analysis of 110 cases from a tertiary care centre in North East India.

Authors:  Rashna Dass Hazarika; Nayan Mani Deka; A B Khyriem; W V Lyngdoh; Himesh Barman; Sourabh Gohain Duwarah; Pankaj Jain; Dibakar Borthakur
Journal:  Indian J Pediatr       Date:  2012-07-22       Impact factor: 1.967

8.  Accuracy of the "traffic light" clinical decision rule for serious bacterial infections in young children with fever: a retrospective cohort study.

Authors:  Sukanya De; Gabrielle J Williams; Andrew Hayen; Petra Macaskill; Mary McCaskill; David Isaacs; Jonathan C Craig
Journal:  BMJ       Date:  2013-02-13
  8 in total

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