OBJECTIVES: To characterize so-called central fatigue, the effect of various levels of exercise on central and peripheral motor potentials were compared. METHODS: Thirteen healthy subjects performed 4 levels of exercise following isometric dorsiflexion of the foot. Post-exercise recordings from the anterior tibial muscle of motor evoked potentials (MEP) evoked by transcranial magnetic stimulation (TMS) and M wave evoked by electrical stimulation of the peroneal nerve were performed. RESULTS: After 5 s the post-exercise MEP amplitude increased. The increase was related to the degree of work performed. Subsequently, there was a gradually decrease of amplitude reaching statistical significance after 15 min. The area of the M wave increased significantly after 10 s and returned to baseline after 2-3 min. CONCLUSIONS: Facilitation and depression of MEP after fatiguing exercise is at least partly a peripheral phenomenon dependent on the level of exercise performed.
OBJECTIVES: To characterize so-called central fatigue, the effect of various levels of exercise on central and peripheral motor potentials were compared. METHODS: Thirteen healthy subjects performed 4 levels of exercise following isometric dorsiflexion of the foot. Post-exercise recordings from the anterior tibial muscle of motor evoked potentials (MEP) evoked by transcranial magnetic stimulation (TMS) and M wave evoked by electrical stimulation of the peroneal nerve were performed. RESULTS: After 5 s the post-exercise MEP amplitude increased. The increase was related to the degree of work performed. Subsequently, there was a gradually decrease of amplitude reaching statistical significance after 15 min. The area of the M wave increased significantly after 10 s and returned to baseline after 2-3 min. CONCLUSIONS: Facilitation and depression of MEP after fatiguing exercise is at least partly a peripheral phenomenon dependent on the level of exercise performed.
Authors: D Lund; A M Ruggiero; S M Ferguson; J Wright; B A English; P A Reisz; S M Whitaker; A C Peltier; R D Blakely Journal: Neuroscience Date: 2010-10-01 Impact factor: 3.590
Authors: Ali Jannati; Mary A Ryan; Harper L Kaye; Melissa Tsuboyama; Alexander Rotenberg Journal: J Clin Neurophysiol Date: 2022-02-01 Impact factor: 2.177