| Literature DB >> 12086886 |
Abstract
The draft human genome sequence and the dissemination of high throughput technology provides opportunities for systematic analysis of cancer cells. Genome-wide mutation screens, high resolution analysis of chromosomal abberations and expression profiling all give comprehensive views of genetic alterations in cancer cells. From these analyses will come a complete list of the genetic changes that drive malignant transformation and of the therapeutic targets that may be exploited for clinical benefit.Entities:
Mesh:
Year: 2002 PMID: 12086886 DOI: 10.1016/s1535-6108(02)00026-0
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743