Literature DB >> 12086884

A matter of life and death.

Douglas R Green1, Gerard I Evan.   

Abstract

We propose that deregulation of proliferation, together with a reduction in apoptosis, creates a platform that is both necessary and can be sufficient for cancer. The secondary traits of diverse neoplasms are a consequence of cell proliferation, tissue expansion, and other outcomes of this platform.

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Year:  2002        PMID： 12086884     DOI： 10.1016/s1535-6108(02)00024-7

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  244 in total

1.  Induction of the Cdk inhibitor p21 by LY83583 inhibits tumor cell proliferation in a p53-independent manner.

Authors:  Dimitri Lodygin; Antje Menssen; Heiko Hermeking
Journal:  J Clin Invest       Date:  2002-12       Impact factor: 14.808

Review 2.  The protein structures that shape caspase activity, specificity, activation and inhibition.

Authors:  Pablo Fuentes-Prior; Guy S Salvesen
Journal:  Biochem J       Date:  2004-12-01       Impact factor: 3.857

Review 3.  Driving apoptosis-relevant proteins toward neural differentiation.

Authors:  Susana Solá; Márcia M Aranha; Cecília M P Rodrigues
Journal:  Mol Neurobiol       Date:  2012-07-01       Impact factor: 5.590

4.  Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression.

Authors:  Jianfang Chen; Haibin Zhou; Angelo Aguilar; Liu Liu; Longchuan Bai; Donna McEachern; Chao-Yie Yang; Jennifer L Meagher; Jeanne A Stuckey; Shaomeng Wang
Journal:  J Med Chem       Date:  2012-10-02       Impact factor: 7.446

5.  c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.

Authors:  Katia M Desbiens; Réna G Deschesnes; Mireille M Labrie; Yan Desfossés; Herman Lambert; Jacques Landry; Kerstin Bellmann
Journal:  Biochem J       Date:  2003-06-01       Impact factor: 3.857

6.  BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.

Authors:  Kristin Tracy; Benjamin C Dibling; Benjamin T Spike; James R Knabb; Paul Schumacker; Kay F Macleod
Journal:  Mol Cell Biol       Date:  2007-06-18       Impact factor: 4.272

Review 7.  Revisiting the hallmarks of cancer.

Authors:  Yousef Ahmed Fouad; Carmen Aanei
Journal:  Am J Cancer Res       Date:  2017-05-01       Impact factor: 6.166

8.  Expression of periostin and its clinicopathological relevance in gastric cancer.

Authors:  Jun-Sheng Li; Guang-Wen Sun; Xiao-Ying Wei; Wen-Hao Tang
Journal:  World J Gastroenterol       Date:  2007-10-21       Impact factor: 5.742

Review 9.  Caspase-independent cell death: leaving the set without the final cut.

Authors:  S W G Tait; D R Green
Journal:  Oncogene       Date:  2008-10-27       Impact factor: 9.867

10.  Autocrine human growth hormone stimulates oncogenicity of endometrial carcinoma cells.

Authors:  Vijay Pandey; Jo K Perry; Kumarasamypet M Mohankumar; Xiang-Jun Kong; Shu-Min Liu; Zheng-Sheng Wu; Murray D Mitchell; Tao Zhu; Peter E Lobie
Journal:  Endocrinology       Date:  2008-05-01       Impact factor: 4.736
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