Literature DB >> 12084345

The role of free prostate-specific antigen in prostate cancer detection.

M Han1, S R Potter, A W Partin.   

Abstract

Prostate-specific antigen (PSA) is the most important serum tumor marker for prostate cancer detection. Free PSA is one of the many molecular forms of PSA that have been identified. Percent free PSA improves the specificity (elimination of unnecessary biopsies) for prostate cancer detection in men with nonsuspicious digital prostate examination and total serum PSA ranges between 4 and 10 ng/mL. Further study is necessary to determine the optimal clinical utility of percent free PSA in men with a total serum PSA level of less than 4 ng/mL. In addition, the level of free PSA may be affected by many factors, including age, prostate volume, prostate manipulation, sample handling, and type of assay used.

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Year:  2000        PMID： 12084345     DOI： 10.1007/s11934-000-0039-8

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN： 1527-2737            Impact factor:   2.862


  39 in total

1.  Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign prostatic disease: a prospective multicenter clinical trial.

Authors:  W J Catalona; A W Partin; K M Slawin; M K Brawer; R C Flanigan; A Patel; J P Richie; J B deKernion; P C Walsh; P T Scardino; P H Lange; E N Subong; R E Parson; G H Gasior; K G Loveland; P C Southwick
Journal:  JAMA       Date:  1998-05-20       Impact factor: 56.272

2.  A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein.

Authors:  H Lilja
Journal:  J Clin Invest       Date:  1985-11       Impact factor: 14.808

3.  Prostate cancer detection in men with serum PSA concentrations of 2.6 to 4.0 ng/mL and benign prostate examination. Enhancement of specificity with free PSA measurements.

Authors:  W J Catalona; D S Smith; D K Ornstein
Journal:  JAMA       Date:  1997-05-14       Impact factor: 56.272

4.  Analysis of percent free prostate-specific antigen (PSA) for prostate cancer detection: influence of total PSA, prostate volume, and age.

Authors:  A W Partin; W J Catalona; P C Southwick; E N Subong; G H Gasior; D W Chan
Journal:  Urology       Date:  1996-12       Impact factor: 2.649

5.  Effect of digital rectal examination and needle biopsy on serum total and percentage of free prostate specific antigen levels.

Authors:  D K Ornstein; G S Rao; D S Smith; T L Ratliff; J W Basler; W J Catalona
Journal:  J Urol       Date:  1997-01       Impact factor: 7.450

6.  Issues in the assessment of prostate-specific antigen immunoassays. An update.

Authors:  R L Vessella; P H Lange
Journal:  Urol Clin North Am       Date:  1997-05       Impact factor: 2.241

Review 7.  The use of prostate-specific antigen and free/total prostate-specific antigen in the diagnosis of localized prostate cancer.

Authors:  A W Partin; H B Carter
Journal:  Urol Clin North Am       Date:  1996-11       Impact factor: 2.241

8.  Free to total prostate-specific antigen (PSA) ratio is superior to total-PSA in differentiating benign prostate hypertrophy from prostate cancer.

Authors:  P J Van Cangh; P De Nayer; P Sauvage; B Tombal; M Elsen; F Lorge; R Opsomer; F X Wese
Journal:  Prostate Suppl       Date:  1996

9.  Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men.

Authors:  William J Catalona; Jerome P Richie; Frederick R Ahmann; M'Liss A Hudson; Peter T Scardino; Robert C Flanigan; Jean B DeKernion; Timothy L Ratliff; Louis R Kavoussi; Bruce L Dalkin; W Bedford Waters; Michael T MacFarlane; Paula C Southwick
Journal:  J Urol       Date:  1994-05       Impact factor: 7.450

10.  Using proportions of free to total prostate-specific antigen, age, and total prostate-specific antigen to predict the probability of prostate cancer.

Authors:  Y T Chen; A A Luderer; R P Thiel; G Carlson; C L Cuny; T F Soriano
Journal:  Urology       Date:  1996-04       Impact factor: 2.649
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  2 in total

1.  The importance of prostate volume in prostate needle biopsy.

Authors:  Ömer Gökhan Doluoğlu; Çetin Volkan Öztekin; Mehmet Karabakan; Alp Özgür Akdemir; Mesut Çetinkaya
Journal:  Turk J Urol       Date:  2013-06

2.  Evaluation of prostatic cancer prevalence in patients with prostatic-specific antigen between 4 and 10 and normal digital rectal examination.

Authors:  Farhad Tadayon; Hamid Reza Arezegar; Mohammad Hatef Khorrami; Rasoul Hashemi Juzdani; Amir Abbas Shahdoost; Mehdi Mellat
Journal:  Adv Biomed Res       Date:  2016-06-20
  2 in total

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