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Literature DB >> 120536

Effects of repeated administration of chlordiazepoxide on spontaneous locomotor activity in mice.

Abstract

Spontaneous locomotor activity has been studied in mice treated with single or repeated doses (five daily injections) of chlordiazepoxide. The repeated administration enhanced the stimulatory action of the lower doses of the drug, while the depressant effect of the higher doses was reduced.

Entities: Chemical Species

Mesh：

Substances：
Chlordiazepoxide

Year: 1979 PMID： 120536 DOI： 10.1007/bf00431999

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

11 in total

1. Chlordiazepoxide effects on reactions to novelty and activity with and without prior drug experience.

Authors: R N Hughes; A M Greig
Journal: Psychopharmacologia Date: 1975-06-19

2. Effects of chlordiazepoxide upon habituation of open-field behavior in white rats.

Authors: S Iwahara; E Sakama
Journal: Psychopharmacologia Date: 1972

3. Modification of depressant and disinhibitory action of flurazepam during short term treatment in the rat.

Authors: G Cannizzaro; S Nigito; P M Provenzano; T Vitikova
Journal: Psychopharmacologia Date: 1972

4. Increase of "antianxiety" activity and tolerance of behavioral depression during chronic administration of oxazepam.

Authors: D L Margules; L Stein
Journal: Psychopharmacologia Date: 1968

5. Effect of d-amphetamine sulphate in combination with CNS depressants on spontaneous motor activity of mice.

Authors: V H Sethy; P Y Naik; U K Sheth
Journal: Psychopharmacologia Date: 1970-08-19

6. Extinction of fear. II. Effects of chlordiazepoxide and chlorpromazine on fear and exploratory behaviour in rats.

Authors: R Kumar
Journal: Psychopharmacologia Date: 1971

7. Effects of centrally acting drugs on exploratory behaviour in rats.

Authors: A S Marriott; P S Spencer
Journal: Br J Pharmacol Chemother Date: 1965-10

8. A comparative study of certain pharmacologic responses following acute and chronic administrations of chlordiazepoxide.

Authors: M E Goldberg; A A Manian; D H Efron
Journal: Life Sci Date: 1967-03-01 Impact factor: 5.037

9. Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized mice.

Authors: M Sansone
Journal: Psychopharmacology (Berl) Date: 1978-10-31 Impact factor: 4.530

10. Enhancement by chlordiazepoxide of the anticholinergic-induced locomotor stimulation in mice.

Authors: M Sansone; J Hano
Journal: Psychopharmacology (Berl) Date: 1979-08-08 Impact factor: 4.530

14 in total

1. Chronic treatment with Ro 15-1788 distinguishes between its benzodiazepine antagonist, agonist and inverse agonist properties.

Authors: S E File; J Dingemanse; H L Friedman; D J Greenblatt
Journal: Psychopharmacology (Berl) Date: 1986 Impact factor: 4.530

2. Facilitation of stimulatory effect of chlordiazepoxide-amphetamine combination by subacute administration of chlordiazepoxide in mice.

Authors: M Sansone; P Renzi; J Vetulani
Journal: Psychopharmacology (Berl) Date: 1986 Impact factor: 4.530

3. Behavioural responses to diazepam of drug-naive and experienced monkeys (Macaca mulatta).

Authors: C M Bradley; A N Nicholson
Journal: Psychopharmacology (Berl) Date: 1986 Impact factor: 4.530

4. Blockade of hoarding in rats by diazepam: an analysis of the anxiety and object value hypotheses of hoarding.

Authors: R K McNamara; I Q Whishaw
Journal: Psychopharmacology (Berl) Date: 1990 Impact factor: 4.530

5. Neuropharmacology of a new potential anxiolytic compound, F 2692, 1-(3'-trifluoromethyl phenyl) 1, 4-dihydro 3-amino 4-oxo 6-methyl pyridazine. 2. Evaluation of its tolerance and dependence producing potential and of its effects on benzodiazepine withdrawal in the elevated plus-maze test in rats.

Authors: P Chopin; M B Assié; M Briley
Journal: Psychopharmacology (Berl) Date: 1993 Impact factor: 4.530

6. Long-lasting single-dose tolerance to neurologic deficits induced by diazepam.

Authors: S A Henauer; E J Gallaher; L E Hollister
Journal: Psychopharmacology (Berl) Date: 1984 Impact factor: 4.530

7. The sedative effects of CL 218,872, like those of chlordiazepoxide, are reversed by benzodiazepine antagonists.

Authors: S E File; S Pellow; L Wilks
Journal: Psychopharmacology (Berl) Date: 1985 Impact factor: 4.530

8. A comparison between chlordiazepoxide and CL 218,872--a synthetic nonbenzodiazepine ligand for benzodiazepine receptors on spontaneous locomotor activity in rats.

Authors: J F McElroy; R L Fleming; R S Feldman
Journal: Psychopharmacology (Berl) Date: 1985 Impact factor: 4.530

9. Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation.

Authors: Graziano Pinna; Roberto C Agis-Balboa; Adrian Zhubi; Kinzo Matsumoto; Dennis R Grayson; Erminio Costa; Alessandro Guidotti
Journal: Proc Natl Acad Sci U S A Date: 2006-03-06 Impact factor: 11.205

10. A possible olfactory component in the effects of diazepam on social behavior of mice.

Authors: A K Dixon
Journal: Psychopharmacology (Berl) Date: 1982 Impact factor: 4.530