Literature DB >> 12052185

Evaluation and development of spinosyns to control ectoparasites on cattle and sheep.

Herbert A Kirst1, Lawrence C Creemer, Sharon A Naylor, Paul T Pugh, Daniel E Snyder, Joseph R Winkle, L Barry Lowe, James T Rothwell, Thomas C Sparks, Thomas V Worden.   

Abstract

The spinosyns are a novel family of fermentation-derived natural products that exhibit potent insecticidal activities. Spinosad, a naturally-occurring mixture of spinosyn A and spinosyn D, has successfully established its utility for crop protective applications in the agrochemical field. Potential applications of this unique chemical family of macrolides also have been investigated in the field of animal health. Applications for the control of blowfly strike and lice on sheep have now been commercially developed and registered in Australia and potential applications for the control of ectoparasites on cattle are being studied.

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Year:  2002        PMID: 12052185     DOI: 10.2174/1568026023393615

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  4 in total

Review 1.  A review on the toxicity and non-target effects of macrocyclic lactones in terrestrial and aquatic environments.

Authors:  Jean-Pierre Lumaret; Faiek Errouissi; Kevin Floate; Jörg Römbke; Keith Wardhaugh
Journal:  Curr Pharm Biotechnol       Date:  2012-05       Impact factor: 2.837

2.  Functional characterization and substrate specificity of spinosyn rhamnosyltransferase by in vitro reconstitution of spinosyn biosynthetic enzymes.

Authors:  Yi-Lin Chen; Yi-Hsine Chen; Yu-Chin Lin; Kuo-Chung Tsai; Hsien-Tai Chiu
Journal:  J Biol Chem       Date:  2009-01-06       Impact factor: 5.157

Review 3.  Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates.

Authors:  Marla Trindade; Leonardo Joaquim van Zyl; José Navarro-Fernández; Ahmed Abd Elrazak
Journal:  Front Microbiol       Date:  2015-08-28       Impact factor: 5.640

Review 4.  Microbial drug discovery: 80 years of progress.

Authors:  Arnold L Demain; Sergio Sanchez
Journal:  J Antibiot (Tokyo)       Date:  2009-01-09       Impact factor: 2.649

  4 in total

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