OBJECTIVE: To evaluate the clinical efficacy of a newly designed Seoul-type keratoprosthesis (S-KPro). METHODS: The S-KPro, which consists of a polymethyl methacrylate optic, a skirt (polyurethane or polypropylene), and polypropylene haptics, was developed and implanted into 2 unsighted and 5 sighted eyes of 7 patients. One patient had a chemical burn, another had an ocular pemphigoid, and the remainder were diagnosed as having Stevens-Johnson syndrome. The preoperative visual acuities ranged from light perception to hand motions. The average follow-up time was 25.6 months. MAIN OUTCOME MEASURES: We evaluated anatomical stability, visual acuity, retinal status, and the visual field. RESULTS: At the last follow-up visit, the S-KPro was well placed in 6 patients. The best-corrected visual acuities of the sighted patients ranged from 20/100 to 20/60 in the affected eye. One patient each experienced retinal detachment or endophthalmitis. Partial extrusion was found in the patient with glaucoma. A retroprosthetic membrane was detected in 1 patient and was treated with an Nd:YAG laser. No glaucomatous visual field defects were found in any of the sighted patients. CONCLUSIONS: Anatomical success was achieved in 6 of 7 eyes. In 3 of the 5 sighted eyes, the S-KPro could rehabilitate corneal blindness not correctable with keratoplasty.
OBJECTIVE: To evaluate the clinical efficacy of a newly designed Seoul-type keratoprosthesis (S-KPro). METHODS: The S-KPro, which consists of a polymethyl methacrylate optic, a skirt (polyurethane or polypropylene), and polypropylene haptics, was developed and implanted into 2 unsighted and 5 sighted eyes of 7 patients. One patient had a chemical burn, another had an ocular pemphigoid, and the remainder were diagnosed as having Stevens-Johnson syndrome. The preoperative visual acuities ranged from light perception to hand motions. The average follow-up time was 25.6 months. MAIN OUTCOME MEASURES: We evaluated anatomical stability, visual acuity, retinal status, and the visual field. RESULTS: At the last follow-up visit, the S-KPro was well placed in 6 patients. The best-corrected visual acuities of the sighted patients ranged from 20/100 to 20/60 in the affected eye. One patient each experienced retinal detachment or endophthalmitis. Partial extrusion was found in the patient with glaucoma. A retroprosthetic membrane was detected in 1 patient and was treated with an Nd:YAG laser. No glaucomatous visual field defects were found in any of the sighted patients. CONCLUSIONS: Anatomical success was achieved in 6 of 7 eyes. In 3 of the 5 sighted eyes, the S-KPro could rehabilitate corneal blindness not correctable with keratoplasty.
Authors: Reeta Huhtinen; Susan Sandeman; Susanna Rose; Elsie Fok; Carol Howell; Linda Fröberg; Niko Moritz; Leena Hupa; Andrew Lloyd Journal: J Mater Sci Mater Med Date: 2013-02-06 Impact factor: 3.896
Authors: David Myung; Nabeel Farooqui; Luo Luo Zheng; Wongun Koh; Sarita Gupta; Amit Bakri; Jaan Noolandi; Jennifer R Cochran; Curtis W Frank; Christopher N Ta Journal: J Biomed Mater Res A Date: 2009-07 Impact factor: 4.396