| Literature DB >> 12047936 |
E Gerhart H Wagner, Klas Flärdh.
Abstract
In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.Mesh:
Substances:
Year: 2002 PMID: 12047936 DOI: 10.1016/s0168-9525(02)02658-6
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639