Literature DB >> 12045352

A practical synthesis of L-ribose.

Masao Akagi1, Daichi Omae, Yoshinori Tamura, Tetsujiro Ueda, Tetsuya Kumashiro, Hidehito Urata.   

Abstract

L-Ribose was synthesized by a simple four-step method with overall yield of 76.3% from a protected L-arabinose derivative, which is a compatible intermediate for the synthesis of L-deoxyribose. The key step of this strategy is the Swern oxidation and subsequent stereoselective reduction accompanied by inversion of the 2-hydroxy group of protected L-arabinose.

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Year:  2002        PMID: 12045352     DOI: 10.1248/cpb.50.866

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  6 in total

1.  Substrate specificity of the Bacillus licheniformis lyxose isomerase YdaE and its application in in vitro catalysis for bioproduction of lyxose and glucose by two-step isomerization.

Authors:  Darshan H Patel; Seung Gon Wi; Seong-Gene Lee; Dae-Seok Lee; Youn-ho Song; Hyeun-Jong Bae
Journal:  Appl Environ Microbiol       Date:  2011-03-18       Impact factor: 4.792

2.  Characterization of a mannose-6-phosphate isomerase from Thermus thermophilus and increased L-ribose production by its R142N mutant.

Authors:  Soo-Jin Yeom; Eun-Sun Seo; Bi-Na Kim; Yeong-Su Kim; Deok-Kun Oh
Journal:  Appl Environ Microbiol       Date:  2010-11-29       Impact factor: 4.792

3.  Substrate specificity of a mannose-6-phosphate isomerase from Bacillus subtilis and its application in the production of L-ribose.

Authors:  Soo-Jin Yeom; Jung-Hwan Ji; Nam-Hee Kim; Chang-Su Park; Deok-Kun Oh
Journal:  Appl Environ Microbiol       Date:  2009-05-15       Impact factor: 4.792

4.  Mirror-image carbohydrates: synthesis of the unnatural enantiomer of a blood group trisaccharide.

Authors:  Fabien P Boulineau; Alexander Wei
Journal:  J Org Chem       Date:  2004-05-14       Impact factor: 4.354

5.  L-ribose production from L-arabinose by using purified L-arabinose isomerase and mannose-6-phosphate isomerase from Geobacillus thermodenitrificans.

Authors:  Soo-Jin Yeom; Nam-Hee Kim; Chang-Su Park; Deok-Kun Oh
Journal:  Appl Environ Microbiol       Date:  2009-09-11       Impact factor: 4.792

Review 6.  Microbial and enzymatic strategies for the production of L-ribose.

Authors:  Ming Chen; Hao Wu; Wenli Zhang; Wanmeng Mu
Journal:  Appl Microbiol Biotechnol       Date:  2020-02-22       Impact factor: 4.813

  6 in total

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