Literature DB >> 12044961

AGEID: a database of aging genes and interventions.

Matt Kaeberlein1, Beatrice Jegalian, Mitch McVey.   

Abstract

The aging genes/interventions database (AGEID) is a database of experimental results related to aging. AGEID is available as part of the science of aging knowledge environment on the World Wide Web at http://sageke.sciencemag.org/cgi/genesdb. The goal of AGEID is to catalog, in one location, every published experiment where life span has been measured in any organism. AGEID also includes information on genes that influence the incidence of age-associated disorders such as Alzheimer's disease and Parkinson's disease. AGEID gene/intervention reports are formatted pages containing the organism and strain background in which the particular experiment was performed, the type of genetic or environmental perturbation, the effect on life span, a description of the gene function and its role in longevity, protein homologs, and references. The use of this database by researchers who study aging should facilitate easy comparison of the genes and interventions that affect life span in different organisms.

Entities:  

Mesh:

Year:  2002        PMID: 12044961     DOI: 10.1016/s0047-6374(02)00011-8

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.432


  11 in total

1.  Protein networks, pleiotropy and the evolution of senescence.

Authors:  Daniel E L Promislow
Journal:  Proc Biol Sci       Date:  2004-06-22       Impact factor: 5.349

2.  AgingDB: A database for oxidative stress and calorie restriction in the study of aging.

Authors:  Dae Ui Park; Chul Hong Kim; Seong Eui Hong; Byung Pal Yu; Hae Young Chung
Journal:  J Am Aging Assoc       Date:  2003-01

Review 3.  Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis.

Authors:  Randa Tao; Athanassios Vassilopoulos; Loukia Parisiadou; Yufan Yan; David Gius
Journal:  Antioxid Redox Signal       Date:  2013-09-14       Impact factor: 8.401

4.  Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

Authors:  Matthew D McGee; Darren Weber; Nicholas Day; Cathy Vitelli; Danielle Crippen; Laura A Herndon; David H Hall; Simon Melov
Journal:  Aging Cell       Date:  2011-05-25       Impact factor: 9.304

5.  Gerontome: a web-based database server for aging-related genes and analysis pipelines.

Authors:  Jekeun Kwon; Byungwook Lee; Haeyoung Chung
Journal:  BMC Genomics       Date:  2010-12-02       Impact factor: 3.969

Review 6.  Genome-wide approaches to understanding human ageing.

Authors:  Matt Kaeberlein
Journal:  Hum Genomics       Date:  2006-06       Impact factor: 4.639

Review 7.  Computational biology for ageing.

Authors:  Daniela Wieser; Irene Papatheodorou; Matthias Ziehm; Janet M Thornton
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-01-12       Impact factor: 6.237

Review 8.  Trajectories of Aging: How Systems Biology in Yeast Can Illuminate Mechanisms of Personalized Aging.

Authors:  Matthew M Crane; Kenneth L Chen; Ben W Blue; Matt Kaeberlein
Journal:  Proteomics       Date:  2019-11-04       Impact factor: 3.984

9.  Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.

Authors:  J R Managbanag; Tarynn M Witten; Danail Bonchev; Lindsay A Fox; Mitsuhiro Tsuchiya; Brian K Kennedy; Matt Kaeberlein
Journal:  PLoS One       Date:  2008-11-25       Impact factor: 3.240

10.  SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression.

Authors:  Kristi Muldoon Jacobs; J Daniel Pennington; Kheem S Bisht; Nukhet Aykin-Burns; Hyun-Seok Kim; Mark Mishra; Lunching Sun; Phuongmai Nguyen; Bong-Hyun Ahn; Jaime Leclerc; Chu-Xia Deng; Douglas R Spitz; David Gius
Journal:  Int J Biol Sci       Date:  2008-09-05       Impact factor: 6.580

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.