Literature DB >> 12039409

Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis.

Brigit A de Jong1, Rudi G J Westendorp, Joyce Eskdale, Bernard M J Uitdehaag, Tom W J Huizinga.   

Abstract

Interleukin-10 (IL-10) secretion affects the inducibility of experimental autoimmune encephalomyelitis and the outcome of multiple sclerosis (MS). Here, we report that a G to A polymorphism in the IL-10 promoter at position -2849 is significantly associated with low IL-10 production. The frequency of this polymorphism is lower among patients with primary progressive compared with patients with relapse-onset MS and control persons.

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Year:  2002        PMID： 12039409     DOI： 10.1016/s0198-8859(02)00369-5

Source DB:  PubMed          Journal:  Hum Immunol        ISSN： 0198-8859            Impact factor:   2.850


  9 in total

1.  FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians.

Authors:  Mohamed M Thabet; J Wesoly; P E Slagboom; R E M Toes; T W J Huizinga
Journal:  Ann Rheum Dis       Date:  2006-12-19       Impact factor: 19.103

2.  Genetic variation of the Fc gamma receptor 3B gene and association with rheumatoid arthritis.

Authors:  Rute B Marques; Mohamed M Thabet; Stefan J White; Jeanine J Houwing-Duistermaat; Aleida M Bakker; Gert-Jan Hendriks; Alexandra Zhernakova; Tom W Huizinga; Annette H van der Helm-van Mil; Rene E Toes
Journal:  PLoS One       Date:  2010-10-05       Impact factor: 3.240

3.  Host Polymorphisms in TLR9 and IL10 Are Associated With the Outcomes of Experimental Haemophilus ducreyi Infection in Human Volunteers.

Authors:  Martin Singer; Wei Li; Servaas A Morré; Sander Ouburg; Stanley M Spinola
Journal:  J Infect Dis       Date:  2016-04-27       Impact factor: 5.226

4.  The diminishment of experimental autoimmune encephalomyelitis (EAE) by neuropeptide alpha-melanocyte stimulating hormone (alpha-MSH) therapy.

Authors:  Andrew W Taylor; Nobuyoshi Kitaichi
Journal:  Brain Behav Immun       Date:  2008-01-02       Impact factor: 7.217

5.  T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis.

Authors:  Chris J Hedegaard; Martin Krakauer; Klaus Bendtzen; Henrik Lund; Finn Sellebjerg; Claus H Nielsen
Journal:  Immunology       Date:  2008-04-04       Impact factor: 7.397

6.  IL-10, IL-6 and CD14 polymorphisms and sepsis outcome in ventilated very low birth weight infants.

Authors:  R John Baier; John Loggins; Krishna Yanamandra
Journal:  BMC Med       Date:  2006-04-12       Impact factor: 8.775

7.  Putative IL-10 Low Producer Genotypes Are Associated with a Favourable Etanercept Response in Patients with Rheumatoid Arthritis.

Authors:  Heiko Schotte; Bernhard Schlüter; Hartmut Schmidt; Markus Gaubitz; Susanne Drynda; Jörn Kekow; Peter Willeke
Journal:  PLoS One       Date:  2015-06-24       Impact factor: 3.240

8.  Evaluation of Interleukin-10 (G-1082A) Promoter Polymorphism in Preeclampsia.

Authors:  Sabnavis Sowmya; Aruna Ramaiah; Tella Sunitha; Pratibha Nallari; Akka Jyothy; Ananthapur Venkateshwari
Journal:  J Reprod Infertil       Date:  2013-04

9.  IL10 haplotype associated with tuberculin skin test response but not with pulmonary TB.

Authors:  Thorsten Thye; Edmund N Browne; Margaret A Chinbuah; John Gyapong; Ivy Osei; Ellis Owusu-Dabo; Norbert W Brattig; Stefan Niemann; Sabine Rüsch-Gerdes; Rolf D Horstmann; Christian G Meyer
Journal:  PLoS One       Date:  2009-05-01       Impact factor: 3.240
  9 in total

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