Literature DB >> 12032032

Propofol reduces spinal motor neuron excitability in humans.

Manabu Kakinohana1, Tatsuya Fuchigami, Seiya Nakamura, Tetsuya Kawabata, Kazuhiro Sugahara.   

Abstract

IMPLICATIONS: We investigated in humans whether changes in spinal motor neuron excitability correlate with the predicted propofol concentration (Cpt) achieved by a target-controlled infusion system. Propofol suppressed F-wave persistence in a Cpt-dependent manner, indicating that propofol depresses spinal motor neuron excitability at clinically relevant concentrations.

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Year:  2002        PMID： 12032032     DOI： 10.1097/00000539-200206000-00040

Source DB:  PubMed          Journal:  Anesth Analg        ISSN： 0003-2999            Impact factor:   5.108


  9 in total

1.  Intraoperative neurophysiological monitoring during complex spinal deformity cases in pediatric patients: methodology, utility, prognostication, and outcome.

Authors:  James Drake; Reinhard Zeller; Abhaya V Kulkarni; Samuel Strantzas; Laura Holmes
Journal:  Childs Nerv Syst       Date:  2010-03-07       Impact factor: 1.475

2.  Nitrous oxide can enhance the hypnotic effect, but not the suppression of spinal motor neuron excitability by propofol in humans.

Authors:  Manabu Kakinohana; Yuji Miyata; Hiroshi Tomiyama; Kazuhiro Sugahara
Journal:  J Anesth       Date:  2006       Impact factor: 2.078

3.  Propofol reduces the amplitude of transcranial electrical motor-evoked potential without affecting spinal motor neurons: a prospective, single-arm, interventional study.

Authors:  Hiroyuki Deguchi; Kenta Furutani; Yusuke Mitsuma; Yoshinori Kamiya; Hiroshi Baba
Journal:  J Anesth       Date:  2021-04-07       Impact factor: 2.078

4.  Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations.

Authors:  Jeremy A Lieberman; John Feiner; Mark Rollins; Russ Lyon; Paul Jasiukaitis
Journal:  J Clin Monit Comput       Date:  2017-08-30       Impact factor: 2.502

5.  The timing of acupuncture stimulation does not influence anesthetic requirement.

Authors:  Grigory Chernyak; Papiya Sengupta; Rainer Lenhardt; Edwin Liem; Anthony G Doufas; Daniel I Sessler; Ozan Akça
Journal:  Anesth Analg       Date:  2005-02       Impact factor: 6.627

6.  Systematic re-evaluation of intraoperative motor-evoked potential suppression in scoliosis surgery.

Authors:  Yew Long Lo; Yam Eng Tan; Sitaram Raman; Adeline Teo; Yang Fang Dan; Chang Ming Guo
Journal:  Scoliosis Spinal Disord       Date:  2018-07-02

7.  Intraoperative responses of motor evoked potentials to the novel intravenous anesthetic remimazolam during spine surgery: a report of two cases.

Authors:  Takashi Kondo; Yukari Toyota; Soshi Narasaki; Tomoyuki Watanabe; Hirotsugu Miyoshi; Noboru Saeki; Yasuo M Tsutsumi
Journal:  JA Clin Rep       Date:  2020-12-09

Review 8.  Effects of general anesthetics on visceral pain transmission in the spinal cord.

Authors:  Yun Wang; Jing Wu; Qing Lin; Hj Nauta; Yun Yue; Li Fang
Journal:  Mol Pain       Date:  2008-10-30       Impact factor: 3.395

9.  An evaluation of anesthetic fade in motor evoked potential monitoring in spinal deformity surgeries.

Authors:  Ryo Ugawa; Tomoyuki Takigawa; Hiroko Shimomiya; Takuma Ohnishi; Yuri Kurokawa; Yoshiaki Oda; Yasuyuki Shiozaki; Haruo Misawa; Masato Tanaka; Toshifumi Ozaki
Journal:  J Orthop Surg Res       Date:  2018-09-05       Impact factor: 2.359
  9 in total

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