Literature DB >> 1203172

The response of the rat liver to alterations in total portal blood flow.

K Weinbren, S L Washington, C Y Smith.   

Abstract

In attempting to isolate the various components involved in the stimulus induced by partial hepatectomy, the effect of sudden increased portal flow to the whole liver has been studied. The technique involved the construction of a portacaval anastomosis and after a week, reconstitution of the original portal vein, allowing resumption of portal blood flow. The effects of increased portal flow in this experiment were to induce hypertrophy of hepatocytes and a minor degree of DNA synthesis.

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Year:  1975        PMID： 1203172      PMCID： PMC2072753     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  18 in total

Review 1.  Liver chalone: a review.

Authors:  M P Stack-Dunne
Journal:  Natl Cancer Inst Monogr       Date:  1973-07

2.  The proliferative response after partial hepatectomy in hypophysectomized rats bearing portacaval anastomoses.

Authors:  K Weinbren; S Washington; F Dowling
Journal:  Br J Exp Pathol       Date:  1973-08

3.  Synchronization of baby rat hepatocytes: a new test for the detection of factors controlling DNA synthesis in rat hepatic cells.

Authors:  C Nadal
Journal:  Cell Tissue Kinet       Date:  1973-09

4.  Hypoglycaemia and the delayed proliferative response after subtotal hepatectomy.

Authors:  K Weinbren; F Dowling
Journal:  Br J Exp Pathol       Date:  1972-02

5.  Effect of protein deprivation and of starvation on DNA synthesis in resting and regenerating rat liver.

Authors:  G Montecuccoli; F Novello; F Stirpe
Journal:  J Nutr       Date:  1972-04       Impact factor: 4.798

6.  The development of a proliferative response in liver parenchyma deprived of portal blood flow.

Authors:  K Weinbren; G A Stirling; S L Washington
Journal:  Br J Exp Pathol       Date:  1972-02

7.  The effects of partial hepatectomy on portal pressure in rats.

Authors:  R H Oliver; P M Sutton
Journal:  Br J Surg       Date:  1966-02       Impact factor: 6.939

8.  Critical cytoplasmic mass and the initiation of the proliferative response in the rat liver.

Authors:  K Weinbren; G A Stirling; S L Washington; S B Hooper; J Laughlin
Journal:  Br J Exp Pathol       Date:  1971-10

9.  Source of the humoral factor that initiates hepatic regeneration.

Authors:  J U Levi; R Zeppa
Journal:  Ann Surg       Date:  1971-09       Impact factor: 12.969

10.  Ultrastructure of STH cells of the pars distalis of hepatectomized mice.

Authors:  J M Llanos; C L Dumm; A C Nessi
Journal:  Z Zellforsch Mikrosk Anat       Date:  1971
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  5 in total

1.  Portal branch ligation in the rat. Reevaluation of a model.

Authors:  J Rozga; B Jeppsson; S Bengmark
Journal:  Am J Pathol       Date:  1986-11       Impact factor: 4.307

2.  Portacaval transposition and subsequent partial hepatectomy in the rat: effects on liver atrophy, hypertrophy and regenerative hyperplasia.

Authors:  J Guest; C J Ryan; I S Benjamin; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-04

3.  Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors.

Authors:  Chandrashekhar R Gandhi; Noriko Murase; Vladimir M Subbotin; Tadahiro Uemura; Michael Nalesnik; Anthony J Demetris; John J Fung; Thomas E Starzl
Journal:  J Hepatol       Date:  2002-09       Impact factor: 25.083

4.  Growth stimulation and apoptosis induced in cultures of neonatal rat liver cells by repeated exposures to epidermal growth factor/urogastrone with or without associated pancreatic hormones.

Authors:  U Armato; F Romano; P G Andreis; L Paccagnella; C Marchesini
Journal:  Cell Tissue Res       Date:  1986       Impact factor: 5.249

5.  Portal hepatotrophic factors, diabetes mellitus and acute liver atrophy, hypertrophy and regeneration.

Authors:  T E Starzl; K A Porter; N Kashiwagi
Journal:  Surg Gynecol Obstet       Date:  1975-12
  5 in total

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