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Literature DB >> 12029646

The effects of portal shunts on intestinal cytochrome P450 3A activity.

Amin Rostami-Hodjegan, Geoffrey T Tucker.

Abstract

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Year: 2002 PMID： 12029646 DOI： 10.1053/jhep.2002.33215

Source DB: PubMed Journal: Hepatology ISSN： 0270-9139 Impact factor: 17.425

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7 in total

1. Reduced duodenal cytochrome P450 3A protein expression and catalytic activity in patients with cirrhosis.

Authors: D J McConn; Y S Lin; T L Mathisen; D K Blough; Y Xu; T Hashizume; S L Taylor; K E Thummel; M C Shuhart
Journal: Clin Pharmacol Ther Date: 2009-02-11 Impact factor: 6.875

2. Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers.

Authors: Margreke J E Brill; Anne van Rongen; Aletta P I Houwink; Jacobus Burggraaf; Bert van Ramshorst; René J Wiezer; Eric P A van Dongen; Catherijne A J Knibbe
Journal: Clin Pharmacokinet Date: 2014-10 Impact factor: 6.447

3. Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.

Authors: Cyrus Ghobadi; Trevor N Johnson; Mohsen Aarabi; Lisa M Almond; Aurel Constant Allabi; Karen Rowland-Yeo; Masoud Jamei; Amin Rostami-Hodjegan
Journal: Clin Pharmacokinet Date: 2011-12-01 Impact factor: 6.447

7. Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.

Authors: Michael Gertz; Catherine M Cartwright; Michael J Hobbs; Kathryn E Kenworthy; Malcolm Rowland; J Brian Houston; Aleksandra Galetin
Journal: Pharm Res Date: 2012-11-22 Impact factor: 4.200

7 in total

The effects of portal shunts on intestinal cytochrome P450 3A activity.

1. Reduced duodenal cytochrome P450 3A protein expression and catalytic activity in patients with cirrhosis.

2. Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers.

3. Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.

4. Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.

5. Statin-Induced Rhabdomyolysis Associated With Transjugular Intrahepatic Portosystemic Shunt Placement.

Review 6. Population-based mechanistic prediction of oral drug absorption.

7. Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.