Literature DB >> 12023110

Recent advances in isocyanide-based multicomponent chemistry.

Alexander Dömling1.   

Abstract

Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of diverse and complex compounds on the one hand and small and 'drug-like' heterocycles on the other hand. No other single synthesis technology enables chemists to search such large chemical spaces as provided by MCRs. MCRs that involve isocyanides are by far the most versatile reactions in terms of scaffolds and number of accessible compounds.

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Year:  2002        PMID： 12023110     DOI： 10.1016/s1367-5931(02)00328-9

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  33 in total

1.  Proceedings of the 2nd International Conference on Multi-Component Reactions, Combinatorial and Related Chemistry, Genoa, 14-16 April 2003.

Authors:  Luca Banfi
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

Review 2.  Chemistry and biology of multicomponent reactions.

Authors:  Alexander Dömling; Wei Wang; Kan Wang
Journal:  Chem Rev       Date:  2012-03-22       Impact factor: 60.622

3.  An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold.

Authors:  M Reza Naimi-Jamal; Sara Mashkouri; Ali Sharifi
Journal:  Mol Divers       Date:  2010-04-07       Impact factor: 2.943

Review 4.  Focusing on shared subpockets - new developments in fragment-based drug discovery.

Authors:  Eman M M Abdelraheem; Carlos J Camacho; Alexander Dömling
Journal:  Expert Opin Drug Discov       Date:  2015-08-21       Impact factor: 6.098

5.  New approach for the synthesis of novel acenaphtho[1,2-b]furan-8-amines.

Authors:  Reza Sandaroos; Saman Damavandi; Mehri Salimi; Ali Mohammadi; Azam Karimian; Maede Hasanpour
Journal:  Mol Divers       Date:  2012-01-25       Impact factor: 2.943

6.  Stereochemical control of the Passerini reaction.

Authors:  Peter R Andreana; Chang C Liu; Stuart L Schreiber
Journal:  Org Lett       Date:  2004-11-11       Impact factor: 6.005

7.  Electrocatalytic multicomponent assembling of isatins, 3-methyl-2-pyrazolin-5-ones and malononitrile: facile and convenient way to functionalized spirocyclic [indole-3,4'-pyrano[2,3-c]pyrazole] system.

Authors:  Michail N Elinson; Alexander S Dorofeev; Fedor M Miloserdov; Gennady I Nikishin
Journal:  Mol Divers       Date:  2008-12-02       Impact factor: 2.943

8.  One-pot synthesis of γ -spiroiminolactones and γ -dispiroiminolactones using N,N'-disubstituted parabanic acid and thioparabanic acid derivatives.

Authors:  Sakineh Asghari; Mohammad Qandalee; Amir Ali Sarmadi
Journal:  Mol Divers       Date:  2016-09-20       Impact factor: 2.943

9.  One-pot synthesis of benzochromeno-pyrazole derivatives.

Authors:  Majid M Heravi; Mina Saeedi; Yahya S Beheshtiha; Hossein A Oskooie
Journal:  Mol Divers       Date:  2010-08-04       Impact factor: 2.943

10.  Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods.

Authors:  Edwin Kroon; Jörg O Schulze; Evelyn Süß; Carlos J Camacho; Ricardo M Biondi; Alexander Dömling
Journal:  Angew Chem Int Ed Engl       Date:  2015-09-04       Impact factor: 15.336
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