Literature DB >> 12010036

Direct catalytic asymmetric alpha-amination of aldehydes.

Benjamin List1.   

Abstract

The first direct catalytic asymmetric alpha-amination of aldehydes is described herein. alpha-Unbranched aldehydes react in this novel proline-catalyzed reaction with dialkyl azodicarboxylates to give alpha-amino aldehydes in excellent yields and enantioselectivities.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12010036     DOI： 10.1021/ja0261325

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  22 in total

1.  New mechanistic studies on the proline-catalyzed aldol reaction.

Authors:  Benjamin List; Linh Hoang; Harry J Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-08       Impact factor: 11.205

2.  α-Amination of keto-nitrones via multihetero-Cope rearrangement employing an imidoyl chloride reagent.

Authors:  Justin T Malinowski; Ericka J Malow; Jeffrey S Johnson
Journal:  Chem Commun (Camb)       Date:  2012-06-26       Impact factor: 6.222

3.  Asymmetric aza-[3+3] annulation in the synthesis of indolizidines: an unexpected reversal of regiochemistry.

Authors:  Grant S Buchanan; Huifang Dai; Richard P Hsung; Aleksey I Gerasyuto; Casi M Scheinebeck
Journal:  Org Lett       Date:  2011-07-25       Impact factor: 6.005

4.  Direct asymmetric amination of α-branched cyclic ketones catalyzed by a chiral phosphoric acid.

Authors:  Xiaoyu Yang; F Dean Toste
Journal:  J Am Chem Soc       Date:  2015-02-26       Impact factor: 15.419

5.  Enantioselective organocatalytic alpha-sulfenylation of substituted diketopiperazines.

Authors:  Nathan W Polaske; Ramin Dubey; Gary S Nichol; Bogdan Olenyuk
Journal:  Tetrahedron Asymmetry       Date:  2009-12-11

6.  Homo-Roche ester derivatives by asymmetric hydrogenation and organocatalysis.

Authors:  Sakunchai Khumsubdee; Hua Zhou; Kevin Burgess
Journal:  J Org Chem       Date:  2013-11-12       Impact factor: 4.354

7.  Enantioselective direct aldol reactions catalyzed by L-prolinamide derivatives.

Authors:  Zhuo Tang; Fan Jiang; Xin Cui; Liu-Zhu Gong; Ai-Qiao Mi; Yao-Zhong Jiang; Yun-Dong Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-12       Impact factor: 11.205

8.  Enantioselective direct α-amination of aldehydes via a photoredox mechanism: a strategy for asymmetric amine fragment coupling.

Authors:  Giuseppe Cecere; Christian M König; Jennifer L Alleva; David W C MacMillan
Journal:  J Am Chem Soc       Date:  2013-07-26       Impact factor: 15.419

9.  Cycle-specific organocascade catalysis: application to olefin hydroamination, hydro-oxidation, and amino-oxidation, and to natural product synthesis.

Authors:  Bryon Simmons; Abbas M Walji; David W C MacMillan
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

10.  3-Hy-droxy-2,2-bis-(1H-pyrazol-1-yl)-cyclo-penta-none.

Authors:  Victor B Rybakov; Anastasia A Utkina; Alexander V Kurkin; Marina A Yurovskaya
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-02-24
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.