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Literature DB >> 12007433

Asthma: T-bet--a master controller?

Abstract

The transcription factors T-bet and GATA3 are important reciprocal determinants of Th1 and Th2 T helper cell differentiation. Recent evidence suggests that these factors may affect airway immunopathology in asthma.

Entities: Chemical

Mesh：

Substances：

Year: 2002 PMID： 12007433 PMCID： PMC3807785 DOI： 10.1016/s0960-9822(02)00830-8

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

20 in total

1. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

Authors: J L Grogan; M Mohrs; B Harmon; D A Lacy; J W Sedat; R M Locksley
Journal: Immunity Date: 2001-03 Impact factor: 31.745

Review 2. Control of T helper cell differentiation--in search of master genes.

Authors: C Dong; R A Flavell
Journal: Sci STKE Date: 2000-09-12

Review 3. Th-2 cytokines in allergic disease.

Authors: D S Robinson
Journal: Br Med Bull Date: 2000 Impact factor: 4.291

4. Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo.

Authors: M C Nawijn; G M Dingjan; R Ferreira; B N Lambrecht; A Karis; F Grosveld; H Savelkoul; R W Hendriks
Journal: J Immunol Date: 2001-07-15 Impact factor: 5.422

5. T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells.

Authors: A A Lighvani; D M Frucht; D Jankovic; H Yamane; J Aliberti; B D Hissong; B V Nguyen; M Gadina; A Sher; W E Paul; J J O'Shea
Journal: Proc Natl Acad Sci U S A Date: 2001-12-18 Impact factor: 11.205

6. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism.

Authors: W Ouyang; S H Ranganath; K Weindel; D Bhattacharya; T L Murphy; W C Sha; K M Murphy
Journal: Immunity Date: 1998-11 Impact factor: 31.745

7. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

Authors: M J Leckie; A ten Brinke; J Khan; Z Diamant; B J O'Connor; C M Walls; A K Mathur; H C Cowley; K F Chung; R Djukanovic; T T Hansel; S T Holgate; P J Sterk; P J Barnes
Journal: Lancet Date: 2000 Dec 23-30 Impact factor: 79.321

8. Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

Authors: S A Bryan; B J O'Connor; S Matti; M J Leckie; V Kanabar; J Khan; S J Warrington; L Renzetti; A Rames; J A Bock; M J Boyce; T T Hansel; S T Holgate; P J Barnes
Journal: Lancet Date: 2000 Dec 23-30 Impact factor: 79.321

9. Efficacy of soluble IL-4 receptor for the treatment of adults with asthma.

Authors: L C Borish; H S Nelson; J Corren; G Bensch; W W Busse; J B Whitmore; J M Agosti
Journal: J Allergy Clin Immunol Date: 2001-06 Impact factor: 10.793

10. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

Authors: A C Mullen; F A High; A S Hutchins; H W Lee; A V Villarino; D M Livingston; A L Kung; N Cereb; T P Yao; S Y Yang; S L Reiner
Journal: Science Date: 2001-06-08 Impact factor: 47.728

16 in total

1. T-bet expression is upregulated in active Behçet's disease.

Authors: B Li; P Yang; H Zhou; Z Zhang; C Xie; X Lin; X Huang; A Kijlstra
Journal: Br J Ophthalmol Date: 2003-10 Impact factor: 4.638

2. Xiaoyin recipe ( ) for psoriasis induces a Th1/Th2 balance drift toward Th2 in peripheral blood mononuclear cells of experimental autoimmune thyroiditis rats.

Authors: Xiao-Guang Xu; Hong Zhang; Xin-Ling Bi; Jun Gu; Yu-Ling Shi; Qiang Hou
Journal: Chin J Integr Med Date: 2012-02-05 Impact factor: 1.978

3. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids.

Authors: Kelan G Tantisira; Eun Sook Hwang; Benjamin A Raby; Eric S Silverman; Stephen L Lake; Brent G Richter; Stanford L Peng; Jeffrey M Drazen; Laurie H Glimcher; Scott T Weiss
Journal: Proc Natl Acad Sci U S A Date: 2004-12-16 Impact factor: 11.205

4. Decreased T-bet expression and changes in chemokine levels in adults with asthma.

Authors: F W S Ko; S W M Lun; C K Wong; C C Szeto; C W K Lam; T F Leung; D S C Hui
Journal: Clin Exp Immunol Date: 2007-03 Impact factor: 4.330

5. The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo.

Authors: S A Ritz; M J Cundall; B U Gajewska; F K Swirski; R E Wiley; D Alvarez; A J Coyle; M R Stampfli; M Jordana
Journal: Clin Exp Immunol Date: 2004-11 Impact factor: 4.330

6. Development of proteoglycan-induced arthritis is independent of IL-17.

Authors: Paul D Doodes; Yanxia Cao; Keith M Hamel; Yumei Wang; Balint Farkas; Yoichiro Iwakura; Alison Finnegan
Journal: J Immunol Date: 2008-07-01 Impact factor: 5.422

7. Differential expression of mRNA for Th1 and Th2 cytokine-associated transcription factors and suppressors of cytokine signalling in peripheral blood mononuclear cells of patients with atopic dermatitis.

Authors: S Arakawa; Y Hatano; K Katagiri
Journal: Clin Exp Immunol Date: 2004-03 Impact factor: 4.330

8. Genetic variation of TBX21 gene increases risk of asthma and its severity in Indian children.

Authors: Neeraj Sharma; Indu Jaiswal; Raju K Mandal; Shubha R Phadke; Shally Awasthi
Journal: J Hum Genet Date: 2014-07-24 Impact factor: 3.172

9. T-bet is induced by interferon-γ to mediate chemokine secretion and migration in human airway smooth muscle cells.

Authors: Cherie A Singer
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2011-01-14 Impact factor: 5.464

Review 10. Microarray profiling of lymphocytes in internal diseases with an altered immune response: potential and methodology.

Authors: Anatoliy Gladkevich; S Adriaan Nelemans; Henk F Kauffman; Jakob Korf
Journal: Mediators Inflamm Date: 2005-12-14 Impact factor: 4.711