Literature DB >> 11999333

Preserved semantic learning in an amnesic patient.

Pat McKenna1, Simon Gerhand.   

Abstract

A case study is reported of an amnesic patient (KN), who displayed an ability to learn a substantial body of new visual and verbal semantic concepts, despite having a severe deficit in episodic memory. In two experiments, using an errorless learning paradigm, he was able to perform at a level close to that of his wife, who served as a control subject. When recall of material was retested after a delay of several months, during which time there were no further learning sessions, his retention was at least as good as, if not better, than that of his wife. This is taken as further evidence for the dissociation of semantic and episodic processes in amnesia. It also provides further evidence for the role of "errorless learning" in efficient acquisition of new facts in amnesia.

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Year:  2002        PMID: 11999333     DOI: 10.1016/s0010-9452(08)70637-3

Source DB:  PubMed          Journal:  Cortex        ISSN: 0010-9452            Impact factor:   4.027


  10 in total

1.  Patients with hippocampal amnesia cannot imagine new experiences.

Authors:  Demis Hassabis; Dharshan Kumaran; Seralynne D Vann; Eleanor A Maguire
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-17       Impact factor: 11.205

2.  Scene construction in amnesia: an FMRI study.

Authors:  Sinéad L Mullally; Demis Hassabis; Eleanor A Maguire
Journal:  J Neurosci       Date:  2012-04-18       Impact factor: 6.167

3.  Imagining fictitious and future experiences: evidence from developmental amnesia.

Authors:  Eleanor A Maguire; Faraneh Vargha-Khadem; Demis Hassabis
Journal:  Neuropsychologia       Date:  2010-07-11       Impact factor: 3.139

4.  MEDIAL TEMPORAL LOBE CONTRIBUTIONS TO FUTURE THINKING: EVIDENCE FROM NEUROIMAGING AND AMNESIA.

Authors:  Mieke Verfaellie; Elizabeth Race; Margaret M Keane
Journal:  Psychol Belg       Date:  2012-09

5.  The effect of hippocampal damage in children on recalling the past and imagining new experiences.

Authors:  Janine M Cooper; Faraneh Vargha-Khadem; David G Gadian; Eleanor A Maguire
Journal:  Neuropsychologia       Date:  2011-03-21       Impact factor: 3.139

6.  The hippocampus and imagining the future: where do we stand?

Authors:  Donna Rose Addis; Daniel L Schacter
Journal:  Front Hum Neurosci       Date:  2012-01-04       Impact factor: 3.169

7.  Non-pharmacological intervention for memory decline.

Authors:  Maria Cotelli; Rosa Manenti; Orazio Zanetti; Carlo Miniussi
Journal:  Front Hum Neurosci       Date:  2012-03-09       Impact factor: 3.169

8.  Episodic memory and executive functions in cognitively healthy individuals display distinct neuroanatomical correlates which are differentially modulated by aging.

Authors:  Raffaele Cacciaglia; José Luis Molinuevo; Gonzalo Sánchez-Benavides; Carles Falcón; Nina Gramunt; Anna Brugulat-Serrat; Oriol Grau; Juan Domingo Gispert
Journal:  Hum Brain Mapp       Date:  2018-07-04       Impact factor: 5.038

9.  Impaired spatial and non-spatial configural learning in patients with hippocampal pathology.

Authors:  Dharshan Kumaran; Demis Hassabis; Hugo J Spiers; Seralynne D Vann; Faraneh Vargha-Khadem; Eleanor A Maguire
Journal:  Neuropsychologia       Date:  2007-04-13       Impact factor: 3.139

10.  Scene construction in developmental amnesia: an fMRI study.

Authors:  Sinéad L Mullally; Faraneh Vargha-Khadem; Eleanor A Maguire
Journal:  Neuropsychologia       Date:  2013-11-11       Impact factor: 3.139

  10 in total

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