Literature DB >> 11997898

Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted reordered turboFLASH magnetic resonance images.

Takao Moteki1, Hiroyuki Horikoshi, Nariyuki Oya, Jun Aoki, Keigo Endo.   

Abstract

PURPOSE: To determine whether the centric reordered snapshot fast low-angle shot (reordered turboFLASH) magnetic resonance (MR) images with no, low, and high motion-probing gradients (MPGs) were useful to evaluate hepatic lesions and hepatic parenchyma.
MATERIALS AND METHODS: The measured diffusion coefficient (D), deviation factor (f), and apparent diffusion coefficient for flowing spin (D*) values for 92 hepatic lesions (33 hepatocellular carcinomas (HCCs), 17 metastases, 27 hemangiomas, and 15 cysts) and the nonlesion-bearing regions of parenchyma in 74 livers (46 noncirrhotic and 28 cirrhotic) were approximately calculated from the reordered turboFLASH images (modified for diffusion sensitivities of b = 0, 50.2, and 295 seconds/mm(2)).
RESULTS: These groups, listed in order of decreasing D* and f values, were cysts, noncirrhotic livers, cirrhotic livers, hemangiomas, metastases, and HCCs. The order on the basis of D values was cysts, hemangiomas, metastases, HCCs, cirrhotic livers, and noncirrhotic livers. Noncirrhotic livers showed higher D* and f values, and lower D values than HCCs and metastases (P < 0.04).
CONCLUSION: The D* and f values, in addition to the D value, may be useful for evaluating the nature of diffusion and flowing spins in hepatic lesions and hepatic parenchyma. Copyright 2002 Wiley-Liss, Inc.

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Year:  2002        PMID: 11997898     DOI: 10.1002/jmri.10101

Source DB:  PubMed          Journal:  J Magn Reson Imaging        ISSN: 1053-1807            Impact factor:   4.813


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