PURPOSE: A new magnetic resonance imaging approach for detection of myocardial late enhancement during free-breathing was developed. METHODS AND RESULTS: For suppression of respiratory motion artifacts, a prospective navigator technology including real-time motion correction and a local navigator restore was implemented. Subject specific inversion times were defined from images with incrementally increased inversion times acquired during a single dynamic scout navigator-gated and real-time motion corrected free-breathing scan. Subsequently, MR-imaging of myocardial late enhancement was performed with navigator-gated and real-time motion corrected adjacent short axis and long axis (two, three and four chamber) views. This alternative approach was investigated in 7 patients with history of myocardial infarction 12 min after i. v. administration of 0.2 mmol/kg body weight gadolinium-DTPA. CONCLUSION: With the presented navigator-gated and real-time motion corrected sequence for MR-imaging of myocardial late enhancement data can be completely acquired during free-breathing. Time constraints of a breath-hold technique are abolished and optimized patient specific inversion time is ensured.
PURPOSE: A new magnetic resonance imaging approach for detection of myocardial late enhancement during free-breathing was developed. METHODS AND RESULTS: For suppression of respiratory motion artifacts, a prospective navigator technology including real-time motion correction and a local navigator restore was implemented. Subject specific inversion times were defined from images with incrementally increased inversion times acquired during a single dynamic scout navigator-gated and real-time motion corrected free-breathing scan. Subsequently, MR-imaging of myocardial late enhancement was performed with navigator-gated and real-time motion corrected adjacent short axis and long axis (two, three and four chamber) views. This alternative approach was investigated in 7 patients with history of myocardial infarction 12 min after i. v. administration of 0.2 mmol/kg body weight gadolinium-DTPA. CONCLUSION: With the presented navigator-gated and real-time motion corrected sequence for MR-imaging of myocardial late enhancement data can be completely acquired during free-breathing. Time constraints of a breath-hold technique are abolished and optimized patient specific inversion time is ensured.
Authors: Mehdi H Moghari; Dana C Peters; Jouke Smink; Lois Goepfert; Kraig V Kissinger; Beth Goddu; Thomas H Hauser; Mark E Josephson; Warren J Manning; Reza Nezafat Journal: Magn Reson Med Date: 2011-02-28 Impact factor: 4.668
Authors: Jaime L Shaw; Benjamin R Knowles; James W Goldfarb; Warren J Manning; Dana C Peters Journal: J Magn Reson Imaging Date: 2013-09-16 Impact factor: 4.813
Authors: Sébastien Roujol; Tamer A Basha; Mehmet Akçakaya; Murilo Foppa; Raymond H Chan; Kraig V Kissinger; Beth Goddu; Sophie Berg; Warren J Manning; Reza Nezafat Journal: Magn Reson Med Date: 2013-10-15 Impact factor: 4.668
Authors: Dana C Peters; Jaime L Shaw; Benjamin R Knowles; Mehdi Hedjazi Moghari; Warren J Manning Journal: J Magn Reson Imaging Date: 2012-11-29 Impact factor: 4.813