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Literature DB >> 11994402

What does Stat3 do?

David E Levy¹, Chien-kuo Lee.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2002 PMID： 11994402 PMCID： PMC150972 DOI： 10.1172/JCI15650

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

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47 in total

1. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival.

Authors: S Sano; Y Takahama; T Sugawara; H Kosaka; S Itami; K Yoshikawa; J Miyazaki; W van Ewijk; J Takeda
Journal: Immunity Date: 2001-08 Impact factor: 31.745

2. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein.

Authors: C L Yu; D J Meyer; G S Campbell; A C Larner; C Carter-Su; J Schwartz; R Jove
Journal: Science Date: 1995-07-07 Impact factor: 47.728

3. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.

Authors: D W Threadgill; A A Dlugosz; L A Hansen; T Tennenbaum; U Lichti; D Yee; C LaMantia; T Mourton; K Herrup; R C Harris
Journal: Science Date: 1995-07-14 Impact factor: 47.728

Review 4. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

Authors: J E Darnell; I M Kerr; G R Stark
Journal: Science Date: 1994-06-03 Impact factor: 47.728

5. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

Authors: C Lütticken; U M Wegenka; J Yuan; J Buschmann; C Schindler; A Ziemiecki; A G Harpur; A F Wilks; K Yasukawa; T Taga
Journal: Science Date: 1994-01-07 Impact factor: 47.728

6. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.

Authors: S Akira; Y Nishio; M Inoue; X J Wang; S Wei; T Matsusaka; K Yoshida; T Sudo; M Naruto; T Kishimoto
Journal: Cell Date: 1994-04-08 Impact factor: 41.582

7. Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

Authors: P L Stein; H Vogel; P Soriano
Journal: Genes Dev Date: 1994-09-01 Impact factor: 11.361

8. Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors.

Authors: R Raz; J E Durbin; D E Levy
Journal: J Biol Chem Date: 1994-09-30 Impact factor: 5.157

9. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

Authors: D Guschin; N Rogers; J Briscoe; B Witthuhn; D Watling; F Horn; S Pellegrini; K Yasukawa; P Heinrich; G R Stark
Journal: EMBO J Date: 1995-04-03 Impact factor: 11.598

10. Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

Authors: A C Greenlund; M A Farrar; B L Viviano; R D Schreiber
Journal: EMBO J Date: 1994-04-01 Impact factor: 11.598

344 in total

Review 1. Stat proteins and oncogenesis.

Authors: Jacqueline Bromberg
Journal: J Clin Invest Date: 2002-05 Impact factor: 14.808

What does Stat3 do?

1. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival.

2. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein.

3. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.

Review 4. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

5. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

6. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.

7. Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

8. Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors.

9. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

10. Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

Review 1. Stat proteins and oncogenesis.

Review 2. Series introduction. JAK-STAT signaling in human disease.

3. Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3.

4. STAT3 tyrosine phosphorylation influences survival in glioblastoma.

5. A novel U-STAT3-dependent mechanism mediates the deleterious effects of chronic nicotine exposure on renal injury.

6. Hepatoprotection via the IL-6/Stat3 pathway.

7. Stat-3 is required for pulmonary homeostasis during hyperoxia.

8. α(1A)-adrenergic receptor differentially regulates STAT3 phosphorylation through PKCϵ and PKCδ in myocytes.

9. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling.

10. The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal.