Literature DB >> 11994044

The cost of gastro-oesophageal reflux disease, dyspepsia and peptic ulcer disease in Sweden.

Lars Agréus1, Lars Borgquist.   

Abstract

BACKGROUND AND
OBJECTIVE: Dyspepsia, peptic ulcer disease (PUD) and gastro-oesophageal reflux disease (GORD) involve a substantial cost to Swedish society. There is a lack of up-to-date nationwide cost estimates after 1985. This study was conducted to present a comprehensive and updated cost analysis and study the change over time of the national cost of these disorders. DESIGN AND
SETTING: Primarily, data from National Swedish databases and secondly, data from databases from the County of Uppsala for 1997 were used for the calculations and estimations. PERSPECTIVE: Swedish societal perspective.
RESULTS: The total cost to Swedish society of dyspepsia, PUD and GORD in 1997 was $US424 million, or $US63 per adult. Direct costs totalled $US258 million (61%) while indirect costs totalled $US166 million (39%). The highest proportions of costs were due to drugs and sick leave, these being 37 and 34%, respectively.
CONCLUSIONS: The cost of dyspepsia and GORD is substantial for patients, health providers and society. Since 1985, drug costs have increased substantially while the cost of sick leave has decreased.

Entities:  

Mesh:

Year:  2002        PMID: 11994044     DOI: 10.2165/00019053-200220050-00006

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  18 in total

1.  Antireflux surgery in Sweden, 1987-1997: a decade of change.

Authors:  R Sandbu; U Haglund; D Arvidsson; T Hallgren
Journal:  Scand J Gastroenterol       Date:  2000-04       Impact factor: 2.423

2.  [Treatment of hypertension at a health center. 2: The patients' expenses in connection with transport and time are more than a tenth of the total treatment costs].

Authors:  M Johannesson; L Borgquist; A Elenstål; B Jönsson; B Tilling
Journal:  Lakartidningen       Date:  1991-03-20

3.  Socio-economic factors, health care consumption and rating of abdominal symptom severity. A report from the abdominal symptom study.

Authors:  L Agréus
Journal:  Fam Pract       Date:  1993-06       Impact factor: 2.267

4.  Natural history of gastroesophageal reflux disease and functional abdominal disorders: a population-based study.

Authors:  L Agréus; K Svärdsudd; N J Talley; M P Jones; G Tibblin
Journal:  Am J Gastroenterol       Date:  2001-10       Impact factor: 10.864

5.  Costs of acid-related disorders to a health maintenance organization.

Authors:  T R Levin; J A Schmittdiel; K Kunz; J M Henning; C J Henke; C J Colby; J V Selby
Journal:  Am J Med       Date:  1997-12       Impact factor: 4.965

6.  Excess sick-listing in nonulcer dyspepsia.

Authors:  O Nyrén; H O Adami; S Gustavsson; L Lööf
Journal:  J Clin Gastroenterol       Date:  1986-06       Impact factor: 3.062

7.  Incidence of peptic ulcer disease in Gothenburg, 1985.

Authors:  I M Schöön; D Mellström; A Odén; B O Ytterberg
Journal:  BMJ       Date:  1989-11-04

8.  General practitioners' approach to dyspepsia. Survey of consultation frequencies, treatment, and investigations.

Authors:  M Heikkinen; P Pikkarainen; J Takala; R Julkunen
Journal:  Scand J Gastroenterol       Date:  1996-07       Impact factor: 2.423

9.  Evaluation of dyspepsia and functional gastrointestinal disorders: a cost-benefit analysis of different approaches.

Authors:  A Sonnenberg; W F Townsend; A D Müller
Journal:  Eur J Gastroenterol Hepatol       Date:  1995-07       Impact factor: 2.566

Review 10.  Clinical economics review: gastrointestinal disease in primary care.

Authors:  R H Jones
Journal:  Aliment Pharmacol Ther       Date:  1996-06       Impact factor: 8.171

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  23 in total

1.  Functional dyspepsia.

Authors:  Rita Brun; Braden Kuo
Journal:  Therap Adv Gastroenterol       Date:  2010-05       Impact factor: 4.409

Review 2.  Cost-of-illness studies : a review of current methods.

Authors:  Ebere Akobundu; Jing Ju; Lisa Blatt; C Daniel Mullins
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

3.  Effects of structured follow-up and of more effective acid inhibitory treatment in the management of GORD patients in a Swedish primary-care setting: a randomized, open-label study.

Authors:  Rickard Ekesbo; Svante Sjöstedt; Heléne Sörngård
Journal:  Clin Drug Investig       Date:  2011       Impact factor: 2.859

4.  Gastro esophageal reflux disease is associated with absence from work: results from a prospective cohort study.

Authors:  Andreas Leodolter; Marc Nocon; Michael Kulig; Stefan N Willich; Peter Malfertheiner; Joachim Labenz
Journal:  World J Gastroenterol       Date:  2005-12-07       Impact factor: 5.742

5.  Functional Dyspepsia Treatment Trial (FDTT): a double-blind, randomized, placebo-controlled trial of antidepressants in functional dyspepsia, evaluating symptoms, psychopathology, pathophysiology and pharmacogenetics.

Authors:  Nicholas J Talley; G Richard Locke; Linda M Herrick; Vickie M Silvernail; Charlene M Prather; Brian E Lacy; John K DiBaise; Colin W Howden; Darren M Brenner; Ernest P Bouras; Hashem B El-Serag; Bincy P Abraham; Paul Moayyedi; Alan R Zinsmeister
Journal:  Contemp Clin Trials       Date:  2012-02-10       Impact factor: 2.226

6.  Comparison of Direct Medical Care Costs Between Erosive Reflux Disease and Non-erosive Reflux Disease in Korean Tertiary Medical Center.

Authors:  Pyoung Ju Seo; Nayoung Kim; Jane C Oh; Byoung Hwan Lee; Cheol Min Shin; Seungchul Suh; Hyunkyung Park; Ryoung Hee Nam; Jin A Cha; Young Soo Park; Dong Ho Lee
Journal:  J Neurogastroenterol Motil       Date:  2010-07-27       Impact factor: 4.924

Review 7.  Changes in gastrointestinal tract function and structure in functional dyspepsia.

Authors:  Hanne Vanheel; Ricard Farré
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-01-15       Impact factor: 46.802

8.  Changes in the prevalence of dyspepsia and Helicobacter pylori infection after 17 years: the Sørreisa gastrointestinal disorder study.

Authors:  Anne Mette Asfeldt; Bjørn Straume; Sonja Eriksson Steigen; Maja-Lisa Løchen; Jon Florholmen; Bjørn Bernersen; Roar Johnsen; Eyvind J Paulssen
Journal:  Eur J Epidemiol       Date:  2008-08-14       Impact factor: 8.082

9.  Proximal Gastric Dysfunction in Functional Dyspepsia: Management Options.

Authors:  Jan Tack
Journal:  Curr Treat Options Gastroenterol       Date:  2004-08

10.  Upper gastrointestinal symptoms, psychosocial co-morbidity and health care seeking in general practice: population based case control study.

Authors:  Linda E Bröker; Gerard J B Hurenkamp; Gerben ter Riet; François G Schellevis; Hans G Grundmeijer; Henk C van Weert
Journal:  BMC Fam Pract       Date:  2009-09-09       Impact factor: 2.497

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