Literature DB >> 11991723

Genomic organization of the interleukin-1 locus.

Scott L Taylor1, Blair R Renshaw, Kirsten E Garka, Dirk E Smith, John E Sims.   

Abstract

Recent additions have expanded the interleukin (IL)-1 gene family to 10 members. We have determined the order, orientation, and intergenic distance of the nine IL-1 family genes that lie on human chromosome 2. We report cDNA sequences for the mouse orthologs of three of these genes. The order and orientation of the mouse genes have been mapped, and the mouse locus compared with the human locus. There is a break in the mouse locus of > 100 kb, compared with the human locus, located between Il1b and the most centromere-proximal of the novel mouse genes. The mouse seems to be missing an ortholog of human IL1F7.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11991723     DOI： 10.1006/geno.2002.6752

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  49 in total

1.  Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir.

Authors:  Jesper F Højen; Thomas A Rasmussen; Karen Lise D Andersen; Anni A Winckelmann; Rune R Laursen; Jesper D Gunst; Holger J Møller; Mayumi Fujita; Lars Østergaard; Ole S Søgaard; Charles A Dinarello; Martin Tolstrup
Journal:  Mol Med       Date:  2015-04-14       Impact factor: 6.354

Review 2.  The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders.

Authors:  H E Barksby; S R Lea; P M Preshaw; J J Taylor
Journal:  Clin Exp Immunol       Date:  2007-06-21       Impact factor: 4.330

3.  Relationships between genetic polymorphisms in inflammation-related factor gene and the pathogenesis of nasopharyngeal cancer.

Authors:  Yan-Li Qu; Hong Yu; Yan-Zhi Chen; Yu-Xia Zhao; Guang-Jun Chen; Lu Bai; Dan Liu; Hong-Xin Su; He-Tong Wang
Journal:  Tumour Biol       Date:  2014-06-22

Review 4.  Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma.

Authors:  Daiju Hu
Journal:  Inflammation       Date:  2017-04       Impact factor: 4.092

5.  IL-36γ/IL-1F9, an innate T-bet target in myeloid cells.

Authors:  Malte Bachmann; Patrick Scheiermann; Lorena Härdle; Josef Pfeilschifter; Heiko Mühl
Journal:  J Biol Chem       Date:  2012-10-24       Impact factor: 5.157

6.  Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy.

Authors:  Lijuan Wang; Yanchun Quan; Yongfang Yue; Xueyuan Heng; Fengyuan Che
Journal:  Oncol Lett       Date:  2018-02-07       Impact factor: 2.967

Review 7.  The IL-1 family: regulators of immunity.

Authors:  John E Sims; Dirk E Smith
Journal:  Nat Rev Immunol       Date:  2010-01-18       Impact factor: 53.106

Review 8.  The IL-33/ST2 pathway: therapeutic target and novel biomarker.

Authors:  Rahul Kakkar; Richard T Lee
Journal:  Nat Rev Drug Discov       Date:  2008-10       Impact factor: 84.694

Review 9.  Interleukin 18 in the CNS.

Authors:  Silvia Alboni; Davide Cervia; Shuei Sugama; Bruno Conti
Journal:  J Neuroinflammation       Date:  2010-01-29       Impact factor: 8.322

10.  An autoinflammatory disease due to homozygous deletion of the IL1RN locus.

Authors:  Sreelatha Reddy; Shuang Jia; Rhonda Geoffrey; Rachel Lorier; Mariko Suchi; Ulrich Broeckel; Martin J Hessner; James Verbsky
Journal:  N Engl J Med       Date:  2009-06-04       Impact factor: 91.245
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.