Literature DB >> 20081871

The IL-1 family: regulators of immunity.

John E Sims1, Dirk E Smith.   

Abstract

Over recent years it has become increasingly clear that innate immune responses can shape the adaptive immune response. Among the most potent molecules of the innate immune system are the interleukin-1 (IL-1) family members. These evolutionarily ancient cytokines are made by and act on innate immune cells to influence their survival and function. In addition, they act directly on lymphocytes to reinforce certain adaptive immune responses. This Review provides an overview of both the long-established and more recently characterized members of the IL-1 family. In addition to their effects on immune cells, their involvement in human disease and disease models is discussed.

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Year:  2010        PMID： 20081871     DOI： 10.1038/nri2691

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  183 in total

1.  Recombinant human IL-1 alpha and -1 beta potentiate IgE-mediated histamine release from human basophils.

Authors:  W A Massey; T C Randall; A Kagey-Sobotka; J A Warner; S M MacDonald; S Gillis; A C Allison; L M Lichtenstein
Journal:  J Immunol       Date:  1989-09-15       Impact factor: 5.422

2.  Role of interleukin 1 in the activation of T lymphocytes.

Authors:  A H Lichtman; J Chin; J A Schmidt; A K Abbas
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

3.  Use of canakinumab in the cryopyrin-associated periodic syndrome.

Authors:  Helen J Lachmann; Isabelle Kone-Paut; Jasmin B Kuemmerle-Deschner; Kieron S Leslie; Eric Hachulla; Pierre Quartier; Xavier Gitton; Albert Widmer; Neha Patel; Philip N Hawkins
Journal:  N Engl J Med       Date:  2009-06-04       Impact factor: 91.245

Review 4.  TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization.

Authors:  Cecilia Garlanda; Hans-Joachim Anders; Alberto Mantovani
Journal:  Trends Immunol       Date:  2009-08-21       Impact factor: 16.687

5.  A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1beta:interleukin-1 receptor antagonist balance in atherosclerosis.

Authors:  Peder S Olofsson; Yuri Sheikine; Ken Jatta; Mehran Ghaderi; Ann Samnegård; Per Eriksson; Allan Sirsjö
Journal:  Circ J       Date:  2009-07-03       Impact factor: 2.993

6.  IL-18 activity in systemic lupus erythematosus.

Authors:  Flavia Favilli; Consuelo Anzilotti; Lucia Martinelli; Paola Quattroni; Salvatore De Martino; Federico Pratesi; Detlef Neumann; Silke Beermann; Daniela Novick; Charles A Dinarello; Diana Boraschi; Paola Migliorini
Journal:  Ann N Y Acad Sci       Date:  2009-09       Impact factor: 5.691

7.  A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses.

Authors:  Guangxun Meng; Fuping Zhang; Ivan Fuss; Atsushi Kitani; Warren Strober
Journal:  Immunity       Date:  2009-06-04       Impact factor: 31.745

8.  Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.

Authors:  Gaby Palmer; Dominique Talabot-Ayer; Céline Lamacchia; Dean Toy; Christian A Seemayer; Sébastien Viatte; Axel Finckh; Dirk E Smith; Cem Gabay
Journal:  Arthritis Rheum       Date:  2009-03

9.  A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

Authors:  Caroline Sutton; Corinna Brereton; Brian Keogh; Kingston H G Mills; Ed C Lavelle
Journal:  J Exp Med       Date:  2006-07-03       Impact factor: 14.307

10.  The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever.

Authors:  Lorenzo Calligaris; Federico Marchetti; Alberto Tommasini; Alessandro Ventura
Journal:  Eur J Pediatr       Date:  2007-06-23       Impact factor: 3.183
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  490 in total

Review 1.  Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity.

Authors:  Patrick J Shaw; Patricia E Ganey; Robert A Roth
Journal:  Toxicol Sci       Date:  2010-06-10       Impact factor: 4.849

2.  The inflammatory cytokine IL-18 induces self-reactive innate antibody responses regulated by natural killer T cells.

Authors:  Sara Lind Enoksson; Emilie K Grasset; Thomas Hägglöf; Nina Mattsson; Ylva Kaiser; Susanne Gabrielsson; Tracy L McGaha; Annika Scheynius; Mikael C I Karlsson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-01       Impact factor: 11.205

3.  Cytokine gene expression profile in monocytic cells after a co-culture with epithelial cells.

Authors:  Libor Kolesar; Eva Brabcova; Eliska Thorburn; Alena Sekerkova; Irena Brabcova; Marcela Jaresova; Ondrej Viklicky; Ilja Striz
Journal:  Immunol Res       Date:  2012-06       Impact factor: 2.829

Review 4.  Into the eye of the cytokine storm.

Authors:  Jennifer R Tisoncik; Marcus J Korth; Cameron P Simmons; Jeremy Farrar; Thomas R Martin; Michael G Katze
Journal:  Microbiol Mol Biol Rev       Date:  2012-03       Impact factor: 11.056

5.  Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice.

Authors:  Lars T Joeckel; Reinhard Wallich; Sunil S Metkar; Christopher J Froelich; Markus M Simon; Christoph Borner
Journal:  J Virol       Date:  2012-06-06       Impact factor: 5.103

6.  Accessory to inflammation.

Authors:  John E Sims
Journal:  Nat Immunol       Date:  2010-10       Impact factor: 25.606

Review 7.  How tolerogenic dendritic cells induce regulatory T cells.

Authors:  Roberto A Maldonado; Ulrich H von Andrian
Journal:  Adv Immunol       Date:  2010       Impact factor: 3.543

Review 8.  Immunology as it pertains to drugs of abuse, AIDS and the neuroimmune axis: mediators and traffic.

Authors:  Thomas J Rogers
Journal:  J Neuroimmune Pharmacol       Date:  2010-10-19       Impact factor: 4.147

9.  Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.

Authors:  Stefan K Drexler; Luca Bonsignore; Mark Masin; Aubry Tardivel; Rene Jackstadt; Heiko Hermeking; Pascal Schneider; Olaf Gross; Jurg Tschopp; Amir S Yazdi
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-22       Impact factor: 11.205

10.  Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.

Authors:  Dominik Schenten; Simone A Nish; Shuang Yu; Xiting Yan; Heung Kyu Lee; Igor Brodsky; Lesley Pasman; Brian Yordy; F Thomas Wunderlich; Jens C Brüning; Hongyu Zhao; Ruslan Medzhitov
Journal:  Immunity       Date:  2014-01-16       Impact factor: 31.745
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