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Literature DB >> 11987749

Rational design of stable lyophilized protein formulations: theory and practice.

John F Carpenter¹, Beyong S Chang, William Garzon-Rodriguez, Theodore W Randolph.

Abstract

Mesh：

Substances：
Excipients
Proteins

Year: 2002 PMID： 11987749 DOI： 10.1007/978-1-4615-0557-0_5

Source DB: PubMed Journal: Pharm Biotechnol ISSN： 1078-0467

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38 in total

1. Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability.

Authors: Maria A Miller; Tarik A Khan; Kevin J Kaczorowski; Brian K Wilson; Aileen K Dinin; Ameya U Borwankar; Miguel A Rodrigues; Thomas M Truskett; Keith P Johnston; Jennifer A Maynard
Journal: J Pharm Sci Date: 2012-07-06 Impact factor: 3.534

2. Conditioning action of the environment on the protein dynamics studied through elastic neutron scattering.

Authors: A Paciaroni; E Cornicchi; A De Francesco; M Marconi; G Onori
Journal: Eur Biophys J Date: 2006-06-08 Impact factor: 1.733

3. Drying-induced variations in physico-chemical properties of amorphous pharmaceuticals and their impact on Stability II: stability of a vaccine.

Authors: Ahmad M Abdul-Fattah; Vu Truong-Le; Luisa Yee; Emilie Pan; Yi Ao; Devendra S Kalonia; Michael J Pikal
Journal: Pharm Res Date: 2007-02-15 Impact factor: 4.200

Rational design of stable lyophilized protein formulations: theory and practice.

1. Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability.

2. Conditioning action of the environment on the protein dynamics studied through elastic neutron scattering.

3. Drying-induced variations in physico-chemical properties of amorphous pharmaceuticals and their impact on Stability II: stability of a vaccine.

4. Formation of stable submicron protein particles by thin film freezing.

Review 5. The Chemistry of Lyophilized Blood Products.

6. Second International Conference on Accelerating Biopharmaceutical Development: March 9-12, 2009, Coronado, CA USA.

7. Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying.

Review 8. Stability of protein pharmaceuticals: an update.

Review 9. Effects of glycosylation on the stability of protein pharmaceuticals.

10. Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide.