Literature DB >> 20065637

Second International Conference on Accelerating Biopharmaceutical Development: March 9-12, 2009, Coronado, CA USA.

Janice M Reichert1, Nitya Jacob, Ashraf Amanullah.   

Abstract

The Second International Conference on Accelerating Biopharmaceutical Development was held in Coronado, California. The meeting was organized by the Society for Biological Engineering (SBE) and the American Institute of Chemical Engineers (AIChE); SBE is a technological community of the AIChE. Bob Adamson (Wyeth) and Chuck Goochee (Centocor) were co-chairs of the event, which had the theme "Delivering cost-effective, robust processes and methods quickly and efficiently." The first day focused on emerging disruptive technologies and cutting-edge analytical techniques. Day two featured presentations on accelerated cell culture process development, critical quality attributes, specifications and comparability, and high throughput protein formulation development. The final day was dedicated to discussion of technology options and new analysis methods provided by emerging disruptive technologies; functional interaction, integration and synergy in platform development; and rapid and economic purification process development.

Entities:  

Mesh:

Year:  2009        PMID: 20065637      PMCID: PMC2726594          DOI: 10.4161/mabs.1.3.8491

Source DB:  PubMed          Journal:  MAbs        ISSN: 1942-0862            Impact factor:   5.857


  40 in total

Review 1.  Very large scale monoclonal antibody purification: the case for conventional unit operations.

Authors:  Brian Kelley
Journal:  Biotechnol Prog       Date:  2007-09-22

2.  High-affinity single-domain binding proteins with a binary-code interface.

Authors:  Akiko Koide; Ryan N Gilbreth; Kaori Esaki; Valentina Tereshko; Shohei Koide
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-09       Impact factor: 11.205

3.  Scientific and legal viability of follow-on protein drugs.

Authors:  David M Dudzinski; Aaron S Kesselheim
Journal:  N Engl J Med       Date:  2008-02-21       Impact factor: 91.245

Review 4.  Applications of mass spectrometry for the structural characterization of recombinant protein pharmaceuticals.

Authors:  Catherine A Srebalus Barnes; Amareth Lim
Journal:  Mass Spectrom Rev       Date:  2007 May-Jun       Impact factor: 10.946

Review 5.  Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.

Authors:  Eugen Koren; Holly W Smith; Elizabeth Shores; Gopi Shankar; Deborah Finco-Kent; Bonita Rup; Yu-Chen Barrett; Viswanath Devanarayan; Boris Gorovits; Shalini Gupta; Thomas Parish; Valerie Quarmby; Michael Moxness; Steven J Swanson; Gary Taniguchi; Linda A Zuckerman; Christopher C Stebbins; Anthony Mire-Sluis
Journal:  J Immunol Methods       Date:  2008-01-29       Impact factor: 2.303

6.  High-throughput process development: determination of dynamic binding capacity using microtiter filter plates filled with chromatography resin.

Authors:  Tryggve Bergander; Kristina Nilsson-Välimaa; Katarina Oberg; Karol M Lacki
Journal:  Biotechnol Prog       Date:  2008-05-03

7.  Selection of pH-related parameters in ion-exchange chromatography using pH-gradient operations.

Authors:  Tangir Ahamed; Sreekanth Chilamkurthi; Beckley K Nfor; Peter D E M Verhaert; Gijs W K van Dedem; Luuk A M van der Wielen; Michel H M Eppink; Emile J A X van de Sandt; Marcel Ottens
Journal:  J Chromatogr A       Date:  2007-12-08       Impact factor: 4.759

8.  Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

Authors:  E Koren; A S De Groot; V Jawa; K D Beck; T Boone; D Rivera; L Li; D Mytych; M Koscec; D Weeraratne; S Swanson; W Martin
Journal:  Clin Immunol       Date:  2007-05-09       Impact factor: 3.969

9.  Structural and functional characterization of disulfide isoforms of the human IgG2 subclass.

Authors:  Thomas M Dillon; Margaret Speed Ricci; Chris Vezina; Gregory C Flynn; Yaoqing Diana Liu; Douglas S Rehder; Matthew Plant; Brad Henkle; Yu Li; Songpon Deechongkit; Brian Varnum; Jette Wypych; Alain Balland; Pavel V Bondarenko
Journal:  J Biol Chem       Date:  2008-03-12       Impact factor: 5.157

10.  Glycosaminoglycans as naturally occurring combinatorial libraries: developing a mass spectrometry-based strategy for characterization of anti-thrombin interaction with low molecular weight heparin and heparin oligomers.

Authors:  Rinat R Abzalimov; Paul L Dubin; Igor A Kaltashov
Journal:  Anal Chem       Date:  2007-07-21       Impact factor: 6.986

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