BACKGROUND: The purpose of this study was to determine the effect of hepatic inflow occlusion (the Pringle maneuver) on laparoscopic radiofrequency (RF) ablation. METHODS: Using a previously validated agarose tissue-mimic model, 1-cm simulated hepatic tumors (three per animal) were laparoscopically ablated in five pigs with normal perfusion and then in five pigs with hepatic artery and portal vein occlusion. Energy was applied until tissue temperature reached 100 degrees C (warm-up) and thereafter for eight min. Specimens were examined immediately after treatment. RESULTS: Vascular occlusion was successful in all cases per color-flow Doppler ultrasound. Pringle time was 11.4 +/- 1.6 min. Warm-up time (2.7 +/- 1.4 vs 20.2 +/- 14.0 min) was significantly faster in the Pringle group. Ablation diameter (34.8 +/- 2.9 vs 24.7 +/- 3.1 mm), proportion of round/ovoid lesions (93% vs 20%), ablation symmetry (100% vs 40%), and margin distance (5.1 +/- 3.0 vs 1.1 +/- 1.2 mm) were significantly better for the Pringle group than the No Pringle group, respectively. CONCLUSION: Using a Pringle maneuver during laparoscopic RF ablation significantly enhances ablation geometry and results in larger margins.
BACKGROUND: The purpose of this study was to determine the effect of hepatic inflow occlusion (the Pringle maneuver) on laparoscopic radiofrequency (RF) ablation. METHODS: Using a previously validated agarose tissue-mimic model, 1-cm simulated hepatic tumors (three per animal) were laparoscopically ablated in five pigs with normal perfusion and then in five pigs with hepatic artery and portal vein occlusion. Energy was applied until tissue temperature reached 100 degrees C (warm-up) and thereafter for eight min. Specimens were examined immediately after treatment. RESULTS:Vascular occlusion was successful in all cases per color-flow Doppler ultrasound. Pringle time was 11.4 +/- 1.6 min. Warm-up time (2.7 +/- 1.4 vs 20.2 +/- 14.0 min) was significantly faster in the Pringle group. Ablation diameter (34.8 +/- 2.9 vs 24.7 +/- 3.1 mm), proportion of round/ovoid lesions (93% vs 20%), ablation symmetry (100% vs 40%), and margin distance (5.1 +/- 3.0 vs 1.1 +/- 1.2 mm) were significantly better for the Pringle group than the No Pringle group, respectively. CONCLUSION: Using a Pringle maneuver during laparoscopic RF ablation significantly enhances ablation geometry and results in larger margins.
Authors: M D Scott DJ; W N Young; L M Watumull; G Lindberg; J B Fleming; R V Rege; R J Brown; D B Jones Journal: J Gastrointest Surg Date: 2000 Nov-Dec Impact factor: 3.452
Authors: L Solbiati; T Ierace; S N Goldberg; S Sironi; T Livraghi; R Fiocca; G Servadio; G Rizzatto; P R Mueller; A Del Maschio; G S Gazelle Journal: Radiology Date: 1997-01 Impact factor: 11.105
Authors: Seung Kwon Kim; Hyo K Lim; Jeong-ah Ryu; Dongil Choi; Won Jae Lee; Ji Yeon Lee; Ju Hyun Lee; Yon Mi Sung; Eun Yoon Cho; Seung-Mo Hong; Jong-Sung Kim Journal: Korean J Radiol Date: 2004 Oct-Dec Impact factor: 3.500
Authors: R Wahba; C Bangard; R Kleinert; S Rösgen; J-H Fischer; K-J Lackner; A H Hölscher; D L Stippel Journal: Langenbecks Arch Surg Date: 2009-03-14 Impact factor: 3.445