| Literature DB >> 11978507 |
Johan W Mouton1, Michael N Dudley, Otto Cars, Hartmut Derendorf, George L Drusano.
Abstract
Over the last decades, the interest in the relationships between the pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents has increased and, therefore, the use of PK/PD indices and expressions has spread widely. The appropriate definition and use of these parameters is a matter of controversy. This paper contains a proposal to use PK/PD expressions for antimicrobial agents and their units in a uniform manner.Entities:
Mesh:
Substances:
Year: 2002 PMID: 11978507 DOI: 10.1016/s0924-8579(02)00031-6
Source DB: PubMed Journal: Int J Antimicrob Agents ISSN: 0924-8579 Impact factor: 5.283