Literature DB >> 11973038

The effect of Gd-DTPA on T(1)-weighted choline signal in human brain tumours.

Philip S Murphy1, Andrzej S K Dzik-Jurasz, Martin O Leach, Ian J Rowland.   

Abstract

The influence of Gd-DTPA on T(1)-weighted (T(1)W) proton MR spectra has been investigated in 19 patients with histologically verified low (n = 13) or high-grade (n = 6) gliomas. Repeat measurements were performed on 9 patients (7 low-grade and 2 high-grade), with 28 examinations performed in total. Comparison of spectra obtained before and after 0.2 mmol/kg Gd-DTPA showed contrast agent induced broadening of the choline signal without significant signal area change. Lack of enhancement of the choline signal with the T(1)-weighted acquisitions implies that the contrast agent and the trimethylamine-containing species do not undergo significant direct interaction. Contrast agent induced changes in the choline signal observed in this and previous studies may, therefore, be attributable to T2*/susceptibility-based effects.

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Year:  2002        PMID： 11973038     DOI： 10.1016/s0730-725x(02)00485-x

Source DB:  PubMed          Journal:  Magn Reson Imaging        ISSN： 0730-725X            Impact factor:   2.546


  5 in total

1.  The effect of paramagnetic contrast in choline peak in patients with glioblastoma multiforme might not be significant.

Authors:  E C Lima; M C G Otaduy; M Tsunemi; R Pincerato; E F Cardoso; S Rosemberg; P H Aguiar; G G Cerri; C C Leite
Journal:  AJNR Am J Neuroradiol       Date:  2012-07-05       Impact factor: 3.825

2.  Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging.

Authors:  Meng Law; Stanley Yang; Hao Wang; James S Babb; Glyn Johnson; Soonmee Cha; Edmond A Knopp; David Zagzag
Journal:  AJNR Am J Neuroradiol       Date:  2003 Nov-Dec       Impact factor: 3.825

3.  Magnetic resonance spectroscopy of the breast at 3T: pre- and post-contrast evaluation for breast lesion characterization.

Authors:  E Kousi; I Tsougos; K Vasiou; K Theodorou; A Poultsidi; I Fezoulidis; C Kappas
Journal:  ScientificWorldJournal       Date:  2012-05-03

4.  The effects of voxel localization and time of echo on the diagnostic accuracy of cystic brain tumors in 3 tesla magnetic resonance spectroscopy.

Authors:  Alireza Rezvanizadeh; Kavous Firouznia; Mohammad Salehi-Sadaghiani; Meisam Mohseni; Dona Gharaei; Hossein Ghanaati; Hamidreza Saligheh Rad; Majid Masoudnia
Journal:  Iran J Radiol       Date:  2012-11-20       Impact factor: 0.212

Review 5.  DCE-MRI, DW-MRI, and MRS in Cancer: Challenges and Advantages of Implementing Qualitative and Quantitative Multi-parametric Imaging in the Clinic.

Authors:  Jessica M Winfield; Geoffrey S Payne; Alex Weller; Nandita M deSouza
Journal:  Top Magn Reson Imaging       Date:  2016-10
  5 in total

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